Self-Protection against the Sphingolipid Biosynthesis Inhibitor Fumonisin B1 Is Conferred by a FUM Cluster-Encoded Ceramide Synthase

S Janevska, I Ferling, K Jojić, J Rautschek, S Hoefgen… - Mbio, 2020 - Am Soc Microbiol
Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect
human and animal health upon consumption, due to the inhibition of ceramide synthase. In …

Glimpsing the chemical composition and the potential of Myrtaceae plant extracts against the food spoilage fungus Thielaviopsis ethacetica

JA Duarte, GAR da Silva, FP Machado, D Folly… - Food Control, 2023 - Elsevier
Food products are susceptible to the action of filamentous fungi (Lima et al., 2021). Fungi
have the singularity of developing complex and differentiated pathogenicity mechanisms …

Peroxiredoxin asp f3 is essential for Aspergillus fumigatus to overcome iron limitation during infection

V Brantl, JM Boysen, A Yap, E Golubtsov, D Ruf… - Mbio, 2021 - Am Soc Microbiol
Aspergillus fumigatus is an important fungal pathogen that causes allergic reactions but also
life-threatening infections. One of the most abundant A. fumigatus proteins is Asp f3. This …

Genetic manipulation of the pneumocandin biosynthetic pathway for generation of analogues and evaluation of their antifungal activity

Y Li, L Chen, Q Yue, X Liu, Z An, GF Bills - ACS Chemical Biology, 2015 - ACS Publications
Pneumocandins are lipohexapeptides of the echinocandin family that potently interrupt
fungal cell wall biogenesis by noncompetitive inhibition of 1, 3-β-glucan synthase. The …

Desaturation of the sphingofungin polyketide tail results in increased serine palmitoyltransferase inhibition

S Hoefgen, AU Bissell, Y Huang, F Gherlone… - Microbiology …, 2022 - Am Soc Microbiol
Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis.
Recently, sphingolipid homeostasis has been connected to several human diseases …

[HTML][HTML] Antifungal potential and biosafety of native plants from the Brazilian Restinga ecosystem

JAD Duarte, SB Fiaux, E Barbosa, PFS Toledo… - Cleaner Engineering …, 2022 - Elsevier
Control of devastating phytopathogens such as the pineapple black rot causing-pathogen
fungus, Thielaviopsis ethacetica, remains dependent on synthetic pesticides despite the …

[HTML][HTML] Chemical composition and antibacterial action of Stryphnodendron pulcherrimum bark extract,“barbatimão” species: evaluation of its use as a topical agent

PWP Gomes, TCDL Pamplona… - Arabian Journal of …, 2021 - Elsevier
Abstract Stryphnodendron pulcherrimum (Willd.) Hochr.(Fabaceae) is a native Amazonian
tree, popularly known as “barbatimão”. The stem barks of this tree are widely used in folk …

Escuzarmycins A–D, Potent Biofungicides to Control Septoria tritici Blotch

I Fernández-Pastor… - Journal of Agricultural …, 2024 - ACS Publications
A study targeting novel antifungal metabolites identified potent in vitro antifungal activity
against key plant pathogens in acetone extracts of Streptomyces sp. strain CA-296093 …

[HTML][HTML] Molecular networking and computational NMR analyses uncover six polyketide-terpene hybrids from termite-associated Xylaria isolates

SR Lee, M Dayras, J Fricke, H Guo, S Balluff… - Communications …, 2024 - nature.com
Fungi constitute the Earth's second most diverse kingdom, however only a small percentage
of these have been thoroughly examined and categorized for their secondary metabolites …

Determination of biological activities of nanoparticles containing silver and copper in water disinfection with/without ultrasound technique

M Fayadoglu, E Fayadoglu, S Er, AT Koparal… - … of Environmental Health …, 2023 - Springer
The final and most crucial step in obtaining clean water is disinfection. More innovative
methods of water disinfection have recently been sought. Water disinfection is a promising …