ROS signalling in the biology of cancer

JN Moloney, TG Cotter - Seminars in cell & developmental biology, 2018 - Elsevier
Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

Edible berries: Bioactive components and their effect on human health

SH Nile, SW Park - Nutrition, 2014 - Elsevier
The importance of food consumption in relation to human health has increased consumer
attention in nutraceutical components and foods, especially fruits and vegetables. Berries …

[HTML][HTML] Colorectal cancer in inflammatory bowel disease: the risk, pathogenesis, prevention and diagnosis

ER Kim, DK Chang - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Patients with inflammatory bowel disease (IBD) are at increased risk for developing
colorectal cancer (CRC), although the overall incidence of IBD-associated CRC has been …

[HTML][HTML] The role of COX-2 in intestinal inflammation and colorectal cancer

D Wang, RN DuBois - Oncogene, 2010 - nature.com
Colorectal cancer (CRC) is a heterogeneous disease, including at least three major forms:
hereditary, sporadic and colitis-associated CRC. A large body of evidence indicates that …

Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro

NP Seeram, LS Adams, Y Zhang, R Lee… - Journal of agricultural …, 2006 - ACS Publications
Berry fruits are widely consumed in our diet and have attracted much attention due to their
potential human health benefits. Berries contain a diverse range of phytochemicals with …

[图书][B] A primer of drug action: A concise nontechnical guide to the actions, uses, and side effects of psychoactive drugs, revised and updated

RM Julien - 2013 - books.google.com
Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the
effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular …

Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs

C Charlier, C Michaux - European journal of medicinal chemistry, 2003 - Elsevier
Dual COX/5-LOX (cyclooxygenase/5-lipoxygenase) inhibitors constitute a valuable
alternative to classical non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 …

[HTML][HTML] Role of prostanoids in gastrointestinal cancer

D Wang, RN DuBois - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Chronic inflammation is a risk factor for gastrointestinal cancer and other diseases. Most
studies have focused on cytokines and chemokines as mediators connecting chronic …

A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas

JA Baron, RS Sandler, RS Bresalier, H Quan, R Riddell… - Gastroenterology, 2006 - Elsevier
Background & Aims: In human and animal studies, nonsteroidal anti-inflammatory drugs
have been associated with a reduced risk of colorectal neoplasia. Although the underlying …

Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy

M Macarthur, GL Hold… - American Journal of …, 2004 - journals.physiology.org
It is well established that cancer arises in chronically inflamed tissue, and this is particularly
notable in the gastrointestinal tract. Classic examples include Helicobacter pylori-associated …