Fatigue in multiple sclerosis–insights into evaluation and management

SS Ayache, MA Chalah - Neurophysiologie Clinique/Clinical …, 2017 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system, characterized by the accumulation of numerous neurological …

15N Hyperpolarization of Dalfampridine at Natural Abundance for Magnetic Resonance Imaging

IV Skovpin, A Svyatova, N Chukanov… - … A European Journal, 2019 - Wiley Online Library
Abstract Signal Amplification by Reversible Exchange (SABRE) is a promising method for
NMR signal enhancement and production of hyperpolarized molecules. As nuclear spin …

A prospective, observational, cohort study to assess the efficacy and safety of prolonged-release fampridine in cognition, fatigue, depression, and quality of life in …

DD Mitsikostas, T Doskas, S Gkatzonis, N Fakas… - Advances in …, 2021 - Springer
Introduction The efficacy of prolonged-release fampridine (PR-FAM) may extend in multiple
sclerosis (MS) beyond walking ability. The objective of this study was to evaluate the effect of …

Long-term effects of prolonged-release fampridine in cognitive function, fatigue, mood and quality of life of MS patients: The IGNITE study

C Bakirtzis, E Konstantinopoulou, DW Langdon… - Journal of the …, 2018 - Elsevier
Background Studies have reported conflicting results regarding the potential benefit of
prolonged release (PR) fampridine in other domains besides walking. Moreover, only a …

[HTML][HTML] What protects adolescents from suicidal attempt: A qualitative study

MR Bazrafshan, F Jahangir, N Shokrpour - Shiraz E-Medical Journal, 2017 - brieflands.com
Background: Suicidal attempts are common among adolescents around the world. Many
countries have taken measures to reduce the high incidence of suicidal attempts and …

Nonwalking response to fampridine in patients with multiple sclerosis in a real-world setting

FA Rodriguez-Leal, R Haase, K Akgün… - … in Chronic Disease, 2019 - journals.sagepub.com
Objectives: Mobility impairments constitute a long-term burden in patients with multiple
sclerosis (MS). Currently there is evidence that the drug fampridine may improve nonwalking …

What Are the Minimal Detectable Changes in SDMT and Verbal Fluency Tests for Assessing Changes in Cognitive Performance in Persons with Multiple Sclerosis …

E Magnin, Y Sagawa, T Moulin, P Decavel - European Neurology, 2020 - karger.com
Introduction: Cognitive impairment is frequent in persons with multiple sclerosis (PwMS) and
can impact on activities of daily living. The capacity to differentiate real changes from …

Effects of prolonged-release fampridine on multiple sclerosis-related gait impairments. a crossover, double-blinded, placebo-controlled study

M Valet, S El Sankari, V Van Pesch, C Detrembleur… - Clinical …, 2021 - Elsevier
Background People with multiple sclerosis have reduced walking speed and impaired gait
pattern. Prolonged release-fampridine is a potassium channel blocker that improves nerve …

[PDF][PDF] Assessment of motor function in patients with multiple sclerosis treated with Fampridine using motor-evoked potentials.

D Trofin, I Onu, C Corciova, C Onita, DM Trofin… - Balneo & PRM …, 2023 - bioclima.ro
1) Background: the purpose of the study is to consider the utility of Transcranial Magnetic
Stimulation (TMS) in patients with Multiple Sclerosis (MS) and walking impairment, treated …

Prolonged-release fampridine as adjunct therapy to active motor training in ms patients: a pilot, double-blind, randomized, placebo-controlled study

F Jacques, A Schembri, A Nativ… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background Both prolonged-release fampridine (PRF) and enabling active motor training
(EAMT) are beneficial in multiple sclerosis (MS) patients. Their combined effect is, however …