The vertebrate limb continues to serve as an influential model of growth, morphogenesis
and pattern formation. With this Review, we aim to give an up-to-date picture of how a …

Limb patterning by Sonic hedgehog (Shh), via either graded spatial or temporal signal
integration, is a paradigm for" morphogen" function, yet how Shh instructs distinct digit …

Sonic Hedgehog (Shh) Is a critical protein in vertebrate development, orchestrating
patterning and growth in many developing systems. First described as a classic morphogen …

Complex signalling between the apical ectodermal ridge (AER-a thickening of the distal
epithelium) and the mesoderm controls limb patterning along the proximo-distal axis …

A fundamental question in biology is how embryonic development is timed between different
species. To address this problem, we compared wing development in the quail and the …

Tissue homeostasis requires a tight control of stem cells to maintain quiescence in normal
conditions, and ensure a balance between progenitor cell production and the need to …

In most tetrapod vertebrates, limb skeletal progenitors condense with postaxial dominance.
Posterior elements (such as ulna and fibula) appear prior to their anterior counterparts …

External bilateral symmetry is a prevalent feature in vertebrates, which emerges during early
embryonic development. To begin with, vertebrate embryos are largely radially symmetric …

Le système nerveux central des vertébrés est constitué d'un assemblage complexe de
nombreux types cellulaires, qui se développent à partir d'un réservoir limité de cellules …

How development is timed between differently sized species is a fundamental question in
biology. To address this problem, we compared wing development in the quail and the …