Traction of 3D and 4D printing in the healthcare industry: from drug delivery and analysis to regenerative medicine

K Osouli-Bostanabad, T Masalehdan… - ACS Biomaterials …, 2022 - ACS Publications
Three-dimensional (3D) printing and 3D bioprinting are promising technologies for a broad
range of healthcare applications from frontier regenerative medicine and tissue engineering …

The endoplasmic reticulum and its contacts: Emerging roles in axon development, neurotransmission, and degeneration

M Kuijpers, PT Nguyen, V Haucke - The Neuroscientist, 2024 - journals.sagepub.com
The neuronal endoplasmic reticulum (ER) consists of a dynamic, tubular network that
extends all the way from the soma into dendrites, axons, and synapses. This morphology …

The role of lipids, lipid metabolism and ectopic lipid accumulation in axon growth, regeneration and repair after CNS injury and disease

D Roy, A Tedeschi - Cells, 2021 - mdpi.com
Axons in the adult mammalian nervous system can extend over formidable distances, up to
one meter or more in humans. During development, axonal and dendritic growth requires …

Neuronal maturation and axon regeneration: unfixing circuitry to enable repair

BJ Hilton, JM Griffin, JW Fawcett… - Nature Reviews …, 2024 - nature.com
Mammalian neurons lose the ability to regenerate their central nervous system axons as
they mature during embryonic or early postnatal development. Neuronal maturation requires …

Neurofilament light protein as a biomarker in depression and cognitive function

N Travica, M Berk, W Marx - Current Opinion in Psychiatry, 2022 - journals.lww.com
Axonal damage is implicated in the neuropathology of depression and cognitive dysfunction.
Consequently, neurofilament light protein is an emerging biomarker with potential in …

Promoting axon regeneration in the central nervous system by increasing PI3-kinase signaling

B Nieuwenhuis, R Eva - Neural Regeneration Research, 2022 - journals.lww.com
Much research has focused on the PI3-kinase and PTEN signaling pathway with the aim to
stimulate repair of the injured central nervous system. Axons in the central nervous system …

Syntaphilin inactivation can enhance axonal mitochondrial transport to improve spinal cord injury

Q Lu, Y Zhang, BOA Botchway, M Huang, X Liu - Molecular Neurobiology, 2023 - Springer
Mitochondria are important organelle of eukaryotic cells. They consists of a large number of
different proteins that provide most of the ATP and supply power for the growth, function, and …

Microfluidic manipulation for biomedical applications in the central and peripheral nervous systems

Z Li, Z Jiang, L Lu, Y Liu - Pharmaceutics, 2023 - mdpi.com
Physical injuries and neurodegenerative diseases often lead to irreversible damage to the
organizational structure of the central nervous system (CNS) and peripheral nervous system …

LRRK2 along the Golgi and lysosome connection: a jamming situation

G Piccoli, M Volta - Biochemical Society Transactions, 2021 - portlandpress.com
Parkinson's disease (PD) is an age-related neurodegenerative disorder, clinically
characterized by bradykinesia, rigidity, and resting tremor. Leucine-Rich Repeat Kinase 2 …

The ANC-1 (Nesprin-1/2) organelle-anchoring protein functions through mitochondria to polarize axon growth in response to SLT-1

NC Fischer, V Friedman, MA Martinez-Reyes… - PLoS …, 2022 - journals.plos.org
A family of giant KASH proteins, including C. elegans ANC-1 and mammalian Nesprin-1 and-
2, are involved in organelle anchoring and are associated with multiple neurodevelopmental …