Structure-based investigations of the NAD+-II riboswitch

Y Lv, J Chang, W Zhang, H Dong, S Chen… - Journal of Agricultural …, 2024 - ACS Publications

Methylated natural products are widely spread in nature. S-Adenosyl-l-methionine (SAM) is
the secondary abundant cofactor and the primary methyl donor, which confer natural …

Crystal structures of the NAD⁺-II riboswitch reveal two distinct ligand-binding pockets

X Peng, W Liao, X Lin, DMJ Lilley… - Nucleic Acids …, 2023 - academic.oup.com

We present crystal structures of a new NAD+-binding riboswitch termed NAD+-II, bound to
nicotinamide mononucleotide (NMN), nicotinamide adenine dinucleotide (NAD+) and …

被引用次数：4 相关文章所有 10 个版本

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[HTML][HTML] A spermidine riboswitch class in bacteria exploits a close variant of an aptamer for the enzyme cofactor S-adenosylmethionine

H Salvail, A Balaji, A Roth, RR Breaker - Cell reports, 2023 - cell.com

Natural polyamines such as spermidine and spermine cations have characteristics that
make them highly likely to be sensed by riboswitches, such as their general affinity to …

Full-Length NAD⁺-I Riboswitches Bind a Single Cofactor but Cannot Discriminate against Adenosine Triphosphate

Y Srivastava, ME Blau, JL Jenkins, JE Wedekind - Biochemistry, 2023 - ACS Publications

Bacterial riboswitches are structured RNAs that bind small metabolites to control
downstream gene expression. Two riboswitch classes have been reported to sense …

[PDF][PDF] 辅酶类核开关的种类, 结构和调控机制研究进展

许笑晨，任艾明 - 自然杂志, 2024 - nature.shu.edu.cn

摘要核开关是一类保守的RNA 元件, 可以通过特异性识别小分子配体来开启或关闭下游相关
基因的表达, 进而调控细胞的生命活动. 目前已鉴定出近60 种核开关, 它们分别识别不同的代谢 …

Research progress on the types, structures and regulation mechanisms of cofactor riboswitches# br

XU Xiaochen, REN Aiming - Chinese Journal of Nature, 2024 - nature.shu.edu.cn

Riboswitches are highly conserved RNA elements capable of recognizing small molecule
ligands and modulating downstream gene expression. To date, nearly 60 types of …