Phage therapy, the therapeutic usage of viruses to treat bacterial infections, has many
theoretical benefits in the 'post antibiotic era.'Nevertheless, there are currently no approved …

The latest WHO report estimates about 1.6 million global deaths annually from TB, which is
further exacerbated by drug-resistant (DR) TB and comorbidities with diabetes and HIV …

Background Tuberculosis remains a huge public health problem and the prolonged
treatment duration obstructs effective tuberculosis control. Higher rifampicin doses have …

The composition of the gastrointestinal microbiota influences systemic immune responses,
but how this affects infectious disease pathogenesis and antibiotic therapy outcome is poorly …

Introduction In light of the ever-escalating problem of antimicrobial resistance, there is an
urgent need for the development of new antimicrobials. In this review, the role of …

The aetiologic agent of tuberculosis (TB), Mycobacterium tuberculosis (Mtb), can survive,
persist, and proliferate in a variety of heterogeneous subcellular compartments. Therefore …

Tuberculosis has been reaffirmed as the infectious disease causing most deaths in the
world. Co-infection with HIV and the increase in multi-drug resistant Mycobacterium …

Indiscriminate use of antibiotics globally has lead to an increase in emergence of drug-
resistant pathogens under both nosocomial, as well as more worryingly, in community …

Monocytes contribute to the pro-inflammatory immune response during the blood stage of a
Plasmodium falciparum infection, but their precise role in malaria pathology is not clear …

In an effort to identify therapeutic intervention strategies for the treatment of COVID-19, we
have investigated a selection of FDA-approved small molecules and biologics that are …