Understanding why pathogenic Mycobacterium avium subsp. paratuberculosis (Map)
isolates cause disparate disease outcomes with differing magnitudes of severity is important …

Background As antibiotic resistance creates a significant global health threat, we need not
only to accelerate the development of novel antibiotics but also to develop better treatment …

Bioavailability is an ancient but effective terminology by which the entire therapeutic efficacy
of a drug directly or indirectly relays. Despite considering general plasma bioavailability …

Background Antibiotic treatments are often associated with a late slowdown in bacterial
killing. This separates the killing of bacteria into at least two distinct phases: a quick phase …

Increasing rifampicin (RIF) dosages could significantly reduce tuberculosis (TB) treatment
durations. Understanding the pharmacokinetic-pharmacodynamics (PK–PD) of increasing …

Introduction: Identification of optimal drug doses and drug combinations is crucial for
optimized treatment of tuberculosis. Areas covered: An unprecedented level of research …

Tubercular infection of the spine is an infection of the vertebral elements by Mycobacterium
tuberculosis or its variants. Like all infections, antimicrobial chemotherapy remains the …

This thesis supports the potential of phages in treating respiratory infections caused by
Staphylococcus aureus bacteria, including MRSA. Phages Koomba kaat 1 and Biyabeda …

Despite the success of antiretroviral therapy roll-out, one-million people still die with HIV-
infection annually. In high-burden settings, tuberculosis remains the most common proximal …

The diseases onchocerciasis and lymphatic filariasis (LF) are a leading cause of global
morbidity affecting over 85.5 million people throughout the tropics. Clinical pathology for …