Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update
JM Kyriakis, J Avruch - Physiological reviews, 2012 - journals.physiology.org
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …
were first elucidated in 1994, and by 2001, substantial progress had been made in …
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
JM Kyriakis, J Avruch - Physiological reviews, 2001 - journals.physiology.org
The molecular details of mammalian stress-activated signal transduction pathways have
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human
Widmann, Christian, Spencer Gibson, Matthew B. Jarpe, and Gary L. Johnson. Mitogen-
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human …
The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions
Y Keshet, R Seger - MAP Kinase Signaling Protocols: Second Edition, 2010 - Springer
Sequential activation of kinases within the mitogen-activated protein (MAP) kinase (MAPK)
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …
Mitogen-activated protein kinases in apoptosis regulation
T Wada, JM Penninger - Oncogene, 2004 - nature.com
Cells are continuously exposed to a variety of environmental stresses and have to decide 'to
be or not to be'depending on the types and strength of stress. Among the many signaling …
be or not to be'depending on the types and strength of stress. Among the many signaling …
Signal transduction through MAP kinase cascades
TS Lewis, PS Shapiro, NG Ahn - Advances in cancer research, 1998 - Elsevier
Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …
Mechanisms of action of cyclosporine
S Matsuda, S Koyasu - Immunopharmacology, 2000 - Elsevier
Cyclosporine (cyclosporin A, CsA) has potent immunosuppressive properties, reflecting its
ability to block the transcription of cytokine genes in activated T cells. It is well established …
ability to block the transcription of cytokine genes in activated T cells. It is well established …
Signal transduction by the c-Jun N-terminal kinase (JNK)—from inflammation to development
YT Ip, RJ Davis - Current opinion in cell biology, 1998 - Elsevier
The c-Jun amino-terminal kinase (JNK) group of MAP kinases has been identified in
mammals and insects. JNK is activated by exposure of cells to cytokines or environmental …
mammals and insects. JNK is activated by exposure of cells to cytokines or environmental …
MAP kinases
Z Chen, TB Gibson, F Robinson, L Silvestro… - Chemical …, 2001 - ACS Publications
MAP Kinases | Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In
Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …
Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …
The Ste20 group kinases as regulators of MAP kinase cascades
I Dan, NM Watanabe, A Kusumi - Trends in cell biology, 2001 - cell.com
Abstract Ste20p (sterile 20 protein) is a putative yeast mitogen-activated protein kinase
kinase kinase kinase (MAP4K) involved in the mating pathway. Its homologs in mammals …
kinase kinase kinase (MAP4K) involved in the mating pathway. Its homologs in mammals …