血管内皮细胞是构成胰岛微环境的重要组成部分. 内皮细胞参与胰腺的发生,
胰腺内分泌细胞的分化和增殖, 胰腺的空间分布等各个方面, 其作用贯穿于胰腺的整个发育过程 …

La régulation glycémique, chez l'humain comme chez l'animal, dépend de la sécrétion
d'insuline. Les différents types de diabète sont ainsi liés à des dysfonctionnements …

The pancreas is a branched, lobular organ consisting of multiple cell types in two separate
tissue compartments that work in concert to maintain proper food digestion and glucose …

Résumé L'objectif du vaste projet de recherche dans lequel s' inscrit ce mémoire est de
guérir le diabète de type 1 en fabriquant un pancréas bioartificiel vascularisé contenant des …

Islet dysfunction is central to the development and progression of type 2 diabetes (T2D).
Epigenetic modifications are essential for establishing and maintaining cell identity and …

Diabetes mellitus (DM) is a disease with epidemic proportions due to increased incidences
worldwide, persistence of undiagnosed cases, uncontrolled forms of the disease …

The incidence of diabetes mellitus has grown exponentially in the last few years.
Etiopathogenesis of diabetes implies a β-cells damage in the islet of Langerhans, either …

Pancreatic islet transplantation exists as an option for treating type I diabetes but is not
widely used as there is a shortage of donors and it requires intensive immunosuppression …