Globally, more than 5 million people die annually from lack of access to critical treatments for
kidney disease—by 2040, chronic kidney disease is projected to be the fifth leading cause of …

Background: Multiple epidemiological studies have shown that exposure to pesticides is
associated with adverse health outcomes. However, the literature on pesticide-related …

The death toll of the epidemic of chronic kidney disease of nontraditional origin (CKDnt) in
Mesoamerica runs into the tens of thousands, affecting mostly young men. There is no …

Multiple epidemics of chronic kidney disease of an unknown etiology (CKDu) have emerged
in agricultural communities around the world. Many factors have been posited as potential …

Background Previous studies have found associations between single toxic metals, such as
arsenic and cadmium, and kidney function in adults with diabetes. However, studies with …

Silica nanoparticles (SiNPs) released during the burning of sugarcane have been
postulated to have a role in chronic kidney disease of unknown etiology. We tested the …

Introduction The incidence of chronic kidney disease of unknown or uncertain etiology
(CKDu) is recognized as a global health crisis. Research to pinpoint the risk factors …

Chronic kidney disease of unknown etiology (CKDu) is an emerging global concern
affecting several agricultural communities in the Americas and South Asia. Environmental …

Copper is a fundamental element for the homeostasis of the body. It is the third most
abundant essential transition metal in humans. Changes in the concentration of copper in …

Abstract Background Arsenic (As), cadmium (Cd) and copper (Cu) are hazardous for kidney
function, while the effects of selenium (Se) and zinc (Zn) were unexplored for the narrow …