Chronic spontaneous urticaria: focus on pathophysiology to unlock treatment advances

A Kaplan, M Lebwohl, AM Giménez‐Arnau, M Hide… - Allergy, 2023 - Wiley Online Library
Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by
intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near …

Anti-IgE for the treatment of chronic urticaria

B Wedi, S Traidl - ImmunoTargets and Therapy, 2021 - Taylor & Francis
Urticaria and angioedema are very common. Management of chronic urticaria subtypes,
which usually persist for many years, is challenging. Recent years have demonstrated that …

Biomarkers of chronic spontaneous urticaria and their clinical implications

R Asero, M Cugno - Expert review of clinical immunology, 2021 - Taylor & Francis
Introduction: Chronic spontaneous urticaria (CSU) is a frequent disorder in which activation
of effector cells and histamine release can be induced via several distinct pathogenetic …

Skin immunosenescence and type 2 inflammation: a mini-review with an inflammaging perspective

B Chen, J Yang, Y Song, D Zhang… - Frontiers in Cell and …, 2022 - frontiersin.org
Skin-resident stromal cells, including keratinocytes, fibroblasts, adipocytes, and immune
cells including Langerhans cells, dendritic cells, T cells, and innate lymphoid cells, and their …

Clinical characterization of patients with chronic spontaneous urticaria according to anti‐TPO IgE levels

J Sánchez, A Sánchez… - Journal of immunology …, 2019 - Wiley Online Library
Background. Chronic spontaneous urticaria (CSU) is a heterogeneous disease with some
frequent comorbidities like autoimmune diseases, drug reactions, and inducible urticaria …

[HTML][HTML] Predicting chronic spontaneous urticaria symptom return after omalizumab treatment discontinuation: exploratory analysis

M Ferrer, A Giménez-Arnau, D Saldana… - The Journal of Allergy …, 2018 - Elsevier
Background Omalizumab is highly effective in controlling chronic spontaneous urticaria
(CSU) symptoms; however, patients can experience symptom return on treatment …

[HTML][HTML] The challenges of chronic urticaria part 2: Pharmacological treatment, chronic inducible urticaria, urticaria in special situations

M Sánchez-Borges, IJ Ansotegui, I Baiardini… - World Allergy …, 2021 - Elsevier
This is Part 2 of an updated follow-up review of the World Allergy Organization (WAO)
position paper on the diagnosis and treatment of urticaria and angioedema. Since that …

Pharmacologic management of chronic urticaria in pediatric patients: the gap between guidelines and practice

PV Williams - Pediatric Drugs, 2020 - Springer
Chronic urticaria is an uncommon disorder in children but can present considerable
morbidity, as well as frustration for the healthcare provider and parent. The prevalence is 0.1 …

[HTML][HTML] Combination therapy with omalizumab and an immune-suppressive agent for resistant chronic spontaneous urticaria-A real-life experience

R Maoz-Segal, T Levy, S Haj-Yahia… - World Allergy …, 2020 - Elsevier
Abstract Background Chronic Spontaneous Urticaria (CSU) is a relatively common immune
mediated disease that can be effectively treated nowadays. Nevertheless, for some patients …

Factors related to omalizumab drug survival and treatment responses in chronic urticaria

E Hasal, E Bulbul Baskan, S Yazici… - International archives of …, 2022 - karger.com
Introduction: This study aimed to evaluate factors affecting drug survival and treatment
response in patients with chronic urticaria treated with omalizumab in clinical practice …