Loss of skeletal muscle mass and strength has recently become a hot research topic with the
extension of life span and an increasingly sedentary lifestyle in modern society …

Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic
regimen of regular exercise and pharmaceutical treatment is often recommended for their …

Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that
causes a decrease in muscle strength and function, and can lead to a reduction in quality of …

Sarcopenia or loss of skeletal muscle mass is the major component of malnutrition and is a
frequent complication in cirrhosis that adversely affects clinical outcomes. These include …

Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …

Sarcopenia is defined as an age associated decline in skeletal muscle mass. The
pathophysiology of sarcopenia is multifactorial, with decreased caloric intake, muscle fiber …

In patients with chronic kidney disease (CKD), loss of cellular proteins increases the risks of
morbidity and mortality. Persistence of muscle protein catabolism in CKD results in striking …

Background Malnutrition/sarcopenia and frailty are common in patients with cirrhosis and
are associated with poor outcomes. Aim To provide an overview of data on the importance …

Metabolic dysfunction contributes to the clinical deterioration observed in advanced cancer
patients and is characterized by weight loss, skeletal muscle wasting, and atrophy of the …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide. Up to one third of individuals with NAFLD will develop nonalcoholic …