Increased global demand for adequate protein nutrition against a backdrop of climate
change and concern for animal agriculture sustainability necessitates new and more …

Background Activation of type IIB activin receptor (ActRIIB) in skeletal muscle leads to
muscle atrophy because of increased muscle protein degradation. However, the intracellular …

Background Acute-on-chronic liver failure (ACLF) is characterized by the development of a
syndrome associated with a high risk of short-term death in patients with acute …

Frailty and sarcopenia are common complications of cirrhosis. Frailty has been described as
an increased susceptibility to stressors secondary to a cumulative decline in physiologic …

Introduction Cancer cachexia is a multifactorial metabolic syndrome associated with a
pathophysiology intertwined with increased inflammatory response, anorexia, metabolic …

Skeletal muscle mass is decreased under a wide range of pathologic conditions. In
particular, chemotherapy is well known for inducing muscle loss and atrophy. Previous …

Simple Summary The benefits of physical exercise against cancer onset and progression, as
well as the adverse effects of physical inactivity have changed the way that we utilize …

Sarcopenia is an important burden in liver cirrhosis representing a negative prognostic
factor for mortality. Moreover, sarcopenia is an independent predictor of complications in …

Inflammatory myopathies, including polymyositis (PM), dermatomyositis (DM), inclusion
body myositis (IBM), necrotizing myopathy (NM), antisynthetase syndrome (ASS) and …

The syndrome of cachexia, ie, involuntary weight loss in patients with underlying diseases,
sarcopenia, ie, loss of muscle mass due to aging, and general muscle atrophy from disuse …