Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer

A Negri, V Naponelli, F Rizzi, S Bettuzzi - Nutrients, 2018 - mdpi.com
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …

Impairing Tumor Metabolic Plasticity via a Stable Metal‐Phenolic‐Based Polymeric Nanomedicine to Suppress Colorectal Cancer

X Li, Z Duan, X Chen, D Pan, Q Luo, L Gu… - Advanced …, 2023 - Wiley Online Library
Targeting metabolic vulnerability of tumor cells is a promising anticancer strategy. However,
the therapeutic efficacy of existing metabolism‐regulating agents is often compromised due …

[HTML][HTML] Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's …

A Cano, M Ettcheto, JH Chang, E Barroso… - Journal of Controlled …, 2019 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG) is a candidate for treatment of Alzheimer's
disease (AD) but its inherent instability limits bioavailability and effectiveness. We found that …

Bioavailability of tea catechins and its improvement

ZY Cai, XM Li, JP Liang, LP Xiang, KR Wang, YL Shi… - Molecules, 2018 - mdpi.com
Many in vitro studies have shown that tea catechins had vevarious health beneficial effects.
However, inconsistent results between in vitro and in vivo studies or between laboratory …

Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement

V Aggarwal, HS Tuli, M Tania, S Srivastava… - Seminars in cancer …, 2022 - Elsevier
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …

Injectable and tissue adhesive EGCG-laden hyaluronic acid hydrogel depot for treating oxidative stress and inflammation

Z He, H Luo, Z Wang, D Chen, Q Feng, X Cao - Carbohydrate Polymers, 2023 - Elsevier
Oxidative stress and inflammation are common pathological mechanisms for the
progression of tissue degeneration. Epigallocatechin-3-gallate (EGCG) features antioxidant …

[HTML][HTML] Improving the stability and bioavailability of tea polyphenols by encapsulations: A review

Z Yin, T Zheng, CT Ho, Q Huang, Q Wu… - Food Science and Human …, 2022 - Elsevier
Tea polyphenols (TPPs) have attracted significant research interest due to their health
benefits. However, TPPs are sensitive to certain environmental and gastrointestinal …

[HTML][HTML] Nanodelivery of natural antioxidants: An anti-aging perspective

A Vaiserman, A Koliada, A Zayachkivska… - … in bioengineering and …, 2020 - frontiersin.org
The aging process is known to be associated with heightened oxidative stress and related
systemic inflammation. Therefore, antioxidant supplementation is regarded as a promising …

A comprehensive review of the potential use of green tea polyphenols in the management of COVID‐19

TE Tallei, Fatimawali, NJ Niode… - Evidence‐Based …, 2021 - Wiley Online Library
Green tea is produced from Camellia sinensis (L.) buds and leaves that have not gone
through the oxidation and withering processes used to produce black and oolong teas. It …