[HTML][HTML] The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Management of clinical chorioamnionitis: an evidence-based approach
This review aimed to examine the existing evidence about interventions proposed for the
treatment of clinical chorioamnionitis, with the goal of developing an evidence-based …
treatment of clinical chorioamnionitis, with the goal of developing an evidence-based …
[HTML][HTML] Evidence that intra-amniotic infections are often the result of an ascending invasion–a molecular microbiological study
Background Microbial invasion of the amniotic cavity resulting in intra-amniotic infection is
associated with obstetrical complications such as preterm labor with intact or ruptured …
associated with obstetrical complications such as preterm labor with intact or ruptured …
Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes
M Kacerovsky, R Romero, M Stepan, J Stranik… - American journal of …, 2020 - Elsevier
Background Preterm prelabor rupture of the membranes (PPROM) is frequently complicated
by intraamniotic inflammatory processes such as intraamniotic infection and sterile …
by intraamniotic inflammatory processes such as intraamniotic infection and sterile …
[HTML][HTML] Chorioamnionitis and risk of long-term neurodevelopmental disorders in offspring: a population-based cohort study
E Tsamantioti, S Lisonkova, G Muraca… - American Journal of …, 2022 - Elsevier
Background Evidence indicates that in utero exposure to chorioamnionitis might increase
the risk of neurodevelopmental disorders in the offspring. However, findings on this topic …
the risk of neurodevelopmental disorders in the offspring. However, findings on this topic …
[HTML][HTML] The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications
The fetus can deploy a local or systemic inflammatory response when exposed to
microorganisms or, alternatively, to non-infection-related stimuli (eg, danger signals or …
microorganisms or, alternatively, to non-infection-related stimuli (eg, danger signals or …
Acute histologic chorioamnionitis independently and directly increases the risk for brain abnormalities seen on magnetic resonance imaging in very preterm infants
Background The independent risk for neurodevelopmental impairments attributed to
chorioamnionitis in premature infants remains controversial. Delayed brain maturation or …
chorioamnionitis in premature infants remains controversial. Delayed brain maturation or …
[HTML][HTML] Clinical chorioamnionitis at term X: microbiology, clinical signs, placental pathology, and neonatal bacteremia–implications for clinical care
Objectives Clinical chorioamnionitis at term is considered the most common infection-related
diagnosis in labor and delivery units worldwide. The syndrome affects 5–12% of all term …
diagnosis in labor and delivery units worldwide. The syndrome affects 5–12% of all term …
Intra-Amniotic Infection with Ureaplasma parvum Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment with Clarithromycin
Intra-amniotic infection is strongly associated with adverse pregnancy and neonatal
outcomes. Most intra-amniotic infections are due to Ureaplasma species; however, the …
outcomes. Most intra-amniotic infections are due to Ureaplasma species; however, the …
[HTML][HTML] Cellular immune responses in amniotic fluid of women with preterm prelabor rupture of membranes
Background Preterm birth is the leading cause of perinatal morbidity and mortality. Preterm
prelabor rupture of membranes (pPROM) occurs in 30% of preterm births; thus, this …
prelabor rupture of membranes (pPROM) occurs in 30% of preterm births; thus, this …