Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture. Autologous blood-derived …

Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

Fibrosis is a major cause of mortality worldwide, characterized by myofibroblast activation
and excessive extracellular matrix deposition. Systemic sclerosis is a prototypic fibrotic …

Background: Atherosclerotic cardiovascular diseases are characterized by a dysregulated
inflammatory and thrombotic state, leading to devastating complications with increased …

Cardiovascular disease remains the main cause of death worldwide. For this reason,
strategies for the primary prevention of atherosclerosis and atherosclerosis-related …

Th cells are the major effector cells in transplant rejection and can be divided into Th1, Th2,
Th17, and Treg subsets. Th differentiation is controlled by transcription factor expression …

Osteoarthritis (OA) is characterized by articular cartilage degeneration in the joints and
results in pain, swelling, stiffness, muscle atrophy, and attendant functional disability. The …

Rationale: Eosinophil β1-integrin activation correlates inversely with FEV1 and directly with
eosinophil-bound P-selectin in subjects with nonsevere allergic asthma. Objectives …

This study aimed at examining the presence and role of chemokines (angiogenic
CCL2/MCP-1 and angiostatic CXCL4/PF-4, CXCL9/Mig, CXCL10/IP-10) in proliferative …

Asymptomatic malaria infections are highly prevalent in malaria endemic regions and most
of these infections remain undiagnosed and untreated. Whereas conventional malaria …