Prostaglandin E2 (PGE2) is the most abundant prostaglandin in the human body. It has a
large number of biological actions that it exerts via four types of receptors, EP1–4. PGE2 is …

Prostaglandins impact on ovarian, uterine, placental, and pituitary function to regulate
reproduction in female livestock. They play important roles in ovulation, luteal function …

Uteroplacental prostaglandins (PGs) play pivotal roles in maintenance and/or termination of
pregnancy in mammals. Regulation of PG biosynthetic and signaling mechanisms in …

This study examines the regulation of major enzymes in prostaglandin E2 (PGE2) synthesis
by glucocorticoids in separate cultures of human amnion epithelial and fibroblast cells at …

Intrauterine infection is still a common trigger of preterm delivery (PTD) and also a
determinant risk factor for the subsequent development of neurodevelopmental …

Context: Prostaglandins are central to the processes of human labor. Prostaglandin E2
(PGE2) synthesized within the uterus mediates cervical ripening and uterine contractions …

In this study we used an isolation/restraint stress to test the hypothesis that stress will affect
the secretion of LH differently in gonadectomised rams and ewes treated with different …

Increased prostaglandin E2 (PGE2) synthesis involves multiple enzymes and two isoforms
of the terminal enzyme of this biosynthetic pathway, PGE synthase (PGES), were recently …

In the dairy cow, puerperal uterine intra-luminal concentrations of PGE2 are related to the
establishment and severity of uterine infections. Here we evaluated whether the blood …

Initiation and maintenance of labor in humans is associated with an increase in
prostaglandin synthesis by intrauterine tissues. The objective of the present study was to …