The healthy microbiome—what is the definition of a healthy gut microbiome?

F Shanahan, TS Ghosh, PW O'Toole - Gastroenterology, 2021 - Elsevier
Use of microbiome-based biomarkers in diagnosis, prognosis, risk profiling, and precision
therapy requires definition of a healthy microbiome in different populations. To determine …

Escherichia coli Residency in the Gut of Healthy Human Adults

JNV Martinson, ST Walk - EcoSal plus, 2020 - Am Soc Microbiol
Escherichia coli is one of the most well-studied bacterial species, but several significant
knowledge gaps remain regarding its ecology and natural history. Specifically, the most …

The person-to-person transmission landscape of the gut and oral microbiomes

M Valles-Colomer, A Blanco-Míguez, P Manghi… - Nature, 2023 - nature.com
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …

Swimming motility of a gut bacterial symbiont promotes resistance to intestinal expulsion and enhances inflammation

TJ Wiles, BH Schlomann, ES Wall, R Betancourt… - PLoS …, 2020 - journals.plos.org
Some of the densest microbial ecosystems in nature thrive within the intestines of humans
and other animals. To protect mucosal tissues and maintain immune tolerance, animal hosts …

Social groups constrain the spatiotemporal dynamics of wild sifaka gut microbiomes

AC Perofsky, L Ancel Meyers, LA Abondano… - Molecular …, 2021 - Wiley Online Library
Primates acquire gut microbiota from conspecifics through direct social contact and shared
environmental exposures. Host behaviour is a prominent force in structuring gut microbial …

Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle

HP Browne, A Almeida, N Kumar, K Vervier, AT Adoum… - Genome Biology, 2021 - Springer
Background Human-to-human transmission of symbiotic, anaerobic bacteria is a
fundamental evolutionary adaptation essential for membership of the human gut microbiota …

Transmission mode and dispersal traits correlate with host specificity in mammalian gut microbes

F Mazel, A Guisan, LW Parfrey - Molecular Ecology, 2024 - Wiley Online Library
Different host species associate with distinct gut microbes in mammals, a pattern sometimes
referred to as phylosymbiosis. However, the processes shaping this host specificity are not …

Social and environmental transmission spread different sets of gut microbes in wild mice

A Raulo, PC Bürkner, GE Finerty, J Dale… - Nature Ecology & …, 2024 - nature.com
Gut microbes shape many aspects of organismal biology, yet how these key bacteria
transmit among hosts in natural populations remains poorly understood. Recent work in …

Host-emitted amino acid cues regulate bacterial chemokinesis to enhance colonization

CD Robinson, EG Sweeney, J Ngo, E Ma, A Perkins… - Cell host & …, 2021 - cell.com
Animal microbiomes are assembled predominantly from environmental microbes, yet the
mechanisms by which individual symbionts regulate their transmission into hosts remain …

Reconstitution and transmission of gut microbiomes and their genes between generations

E Rosenberg, I Zilber-Rosenberg - Microorganisms, 2021 - mdpi.com
Microbiomes are transmitted between generations by a variety of different vertical and/or
horizontal modes, including vegetative reproduction (vertical), via female germ cells …