5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …

A critical period is a developmental epoch during which the nervous system is expressly
sensitive to specific environmental stimuli that are required for proper circuit organization …

Highlights•Acetylcholine, noradrenaline, dopamine and serotonin all facilitate long-term
synaptic plasticity.•Neuromodulators facilitate long-term synaptic plasticity by common and …

Neurodegenerative diseases represent nowadays one of the major health problems.
Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not …

The serotonergic system is involved in diverse cognitive functions including memory. Of
particular importance to daily life are declarative memories that contain information about …

Abstract Bacopa monnieri (L.)–(BM) is a perennial, creeping herb which is widely used in
traditional ayurvedic medicine as a neural tonic to improve intelligence and memory …

The constitutive activity of different serotonin receptors (5-HTRs) toward intracellular
signaling pathways has been proposed to have physiological and pathological importance …

Importance The cerebral serotonin 4 (5-HT 4) receptor is a promising novel target for
treatment of major depressive disorder (MDD), and pharmacological stimulation of the 5-HT …

Cognitive deficits commonly accompany psychiatric disorders but are often
underrecognised, and difficult to treat. The 5-HT 4 receptor is a promising potential treatment …