Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
Bioprinting: From Tissue and Organ Development to in Vitro Models
Bioprinting techniques have been flourishing in the field of biofabrication with pronounced
and exponential developments in the past years. Novel biomaterial inks used for the …
and exponential developments in the past years. Novel biomaterial inks used for the …
Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such
procedures are normally invasive and difficult to perform. Here, we develop and test a …
procedures are normally invasive and difficult to perform. Here, we develop and test a …
Biofabrication strategies for 3D in vitro models and regenerative medicine
Organs are complex systems composed of different cells, proteins and signalling molecules
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …
[HTML][HTML] Bioinks and bioprinting technologies to make heterogeneous and biomimetic tissue constructs
The native tissues are complex structures consisting of different cell types, extracellular
matrix materials, and biomolecules. Traditional tissue engineering strategies have not been …
matrix materials, and biomolecules. Traditional tissue engineering strategies have not been …
Breaking the resolution limits of 3D bioprinting: future opportunities and present challenges
Bioprinting aims to produce 3D structures from which embedded cells can receive
mechanical and chemical stimuli that influence their behavior, direct their organization and …
mechanical and chemical stimuli that influence their behavior, direct their organization and …
Large cardiac muscle patches engineered from human induced-pluripotent stem cell–derived cardiac cells improve recovery from myocardial infarction in swine
Background: Here, we generated human cardiac muscle patches (hCMPs) of clinically
relevant dimensions (4 cm× 2 cm× 1.25 mm) by suspending cardiomyocytes, smooth muscle …
relevant dimensions (4 cm× 2 cm× 1.25 mm) by suspending cardiomyocytes, smooth muscle …
Guiding lights: tissue bioprinting using photoactivated materials
Photoactivated materials have found widespread use in biological and medical applications
and are playing an increasingly important role in the nascent field of three-dimensional (3D) …
and are playing an increasingly important role in the nascent field of three-dimensional (3D) …
4D physiologically adaptable cardiac patch: A 4-month in vivo study for the treatment of myocardial infarction
H Cui, C Liu, T Esworthy, Y Huang, Z Yu, X Zhou… - Science …, 2020 - science.org
There has been considerable progress in engineering cardiac scaffolds for the treatment of
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …
3D bioprinting of functional tissue models for personalized drug screening and in vitro disease modeling
Abstract 3D bioprinting is emerging as a promising technology for fabricating complex tissue
constructs with tailored biological components and mechanical properties. Recent advances …
constructs with tailored biological components and mechanical properties. Recent advances …