Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction

SJ Park, RY Kim, BW Park, S Lee, SW Choi… - Nature …, 2019 - nature.com
Since both myocardium and vasculature in the heart are excessively damaged following
myocardial infarction (MI), therapeutic strategies for treating MI hearts should concurrently …

Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Advances on bone substitutes through 3D bioprinting

T Genova, I Roato, M Carossa, C Motta… - International journal of …, 2020 - mdpi.com
Reconstruction of bony defects is challenging when conventional grafting methods are used
because of their intrinsic limitations (biological cost and/or biological properties). Bone …

A minimally invasive exosome spray repairs heart after myocardial infarction

J Yao, K Huang, D Zhu, T Chen, Y Jiang, J Zhang… - ACS …, 2021 - ACS Publications
Myocardial infarction (MI) remains the most common cause of death worldwide. Many MI
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …

An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs

K Huang, EW Ozpinar, T Su, J Tang, D Shen… - Science translational …, 2020 - science.org
Cell therapy has been a promising strategy for cardiac repair after injury or infarction;
however, low retention and engraftment of transplanted cells limit potential therapeutic …

Guiding lights: tissue bioprinting using photoactivated materials

M Lee, R Rizzo, F Surman, M Zenobi-Wong - Chemical Reviews, 2020 - ACS Publications
Photoactivated materials have found widespread use in biological and medical applications
and are playing an increasingly important role in the nascent field of three-dimensional (3D) …

[HTML][HTML] 3D bioprinting: a novel avenue for manufacturing tissues and organs

B Zhang, L Gao, L Ma, Y Luo, H Yang, Z Cui - Engineering, 2019 - Elsevier
Abstract Three-dimensional (3D) bioprinting is a rapidly growing technology that has been
widely used in tissue engineering, disease studies, and drug screening. It provides the …

Biomaterial-free three-dimensional bioprinting of cardiac tissue using human induced pluripotent stem cell derived cardiomyocytes

CS Ong, T Fukunishi, H Zhang, CY Huang, A Nashed… - Scientific reports, 2017 - nature.com
We have developed a novel method to deliver stem cells using 3D bioprinted cardiac
patches, free of biomaterials. Human induced pluripotent stem cell-derived cardiomyocytes …

4D physiologically adaptable cardiac patch: a 4-month in vivo study for the treatment of myocardial infarction

H Cui, C Liu, T Esworthy, Y Huang, Z Yu, X Zhou… - Science …, 2020 - science.org
There has been considerable progress in engineering cardiac scaffolds for the treatment of
myocardial infarction (MI). However, it is still challenging to replicate the structural specificity …

UV-assisted 3D bioprinting of nanoreinforced hybrid cardiac patch for myocardial tissue engineering

M Izadifar, D Chapman, P Babyn, X Chen… - … Engineering Part C …, 2018 - liebertpub.com
Biofabrication of cell supportive cardiac patches that can be directly implanted on
myocardial infarct is a potential solution for myocardial infarction repair. Ideally, cardiac …