As the organ with the highest demand for oxygen, the brain has a poor tolerance to ischemia
and hypoxia. Despite severe ischemia/hypoxia induces the occurrence and development of …

Remote ischemic conditioning (RIC) is the application of brief periods of ischemia to an
organ or tissue with the aim of inducing protection from ischemia in a distant organ. It was …

Even though ischemic stroke is among the leading causes of death worldwide, the
pathogenic mechanisms underlying ischemia reperfusion (I/R) brain injury remain unclear …

Cerebral ischemia (CI) results from inadequate blood flow to the brain. The difficulty of
delivering therapeutic molecules to lesions resulting from CI hinders the effective treatment …

Remote ischemic conditioning (RIC) is a promising therapeutic approach for ischemic stroke
patients. It has been proven that RIC reduces infarct size and improves functional outcomes …

Background Remote ischemic conditioning (RIC) by brief periods of limb ischemia and
reperfusion protects against ischemia–reperfusion injury. We studied the cardioprotective …

Remote ischemic conditioning (RIC) is a promising neuroprotective therapy for ischemic
stroke. Preclinical studies investigating RIC have shown RIC reduced infarct volume, but …

Insulin-like growth factor 1 (IGF-1) has neuroprotective actions, including vasodilatory, anti-
inflammatory, and antithrombotic effects, following ischemic stroke. However, the molecular …

Remote ischaemic conditioning (RIC) is achieved by repeated transient ischaemia of a
distant organ/limb and is neuroprotective in experimental ischaemic stroke. However, the …

There remain debates on neuroprotection and rehabilitation techniques for acute ischemic
stroke patients. Therapeutic physical exercise following stroke has shown promise but is …