Acute respiratory distress syndrome (ARDS) is associated with a heterogeneous pattern of
injury throughout the lung parenchyma that alters regional alveolar opening and collapse …

A hallmark of ARDS is progressive shrinking of the 'baby lung,'now referred to as the
ventilator-induced lung injury (VILI)'vortex.'Reducing the risk of the VILI vortex is the goal of …

Acute respiratory distress syndrome (ARDS) afflicts 200,000 patients annually with a
mortality rate of 30% to 60% despite wide use of low tidal volume (LTV) ventilation, the …

Secretion of pulmonary surfactant that maintains low surface tension within the lung is
primarily mediated by mechanical stretching of alveolar epithelial type II (AEII) cells. We …

Introduction When alveoli collapse the traction forces exerted on their walls by adjacent
expanded units may increase and concentrate. These forces may promote its re-expansion …

Background Positive end-expiratory pressure (PEEP) individualized to a maximal respiratory
system compliance directly implies minimal driving pressures with potential outcome …

Mechanical ventilation is a risk factor for the development of bronchopulmonary dysplasia in
premature infants. Fifteen minutes of high tidal volume (Vt) ventilation induces inflammatory …

Premature infants exposed to ventilation are at risk of developing bronchopulmonary
dysplasia and persistent lung disease in childhood. We report where injury occurred within …

Ventilator-induced lung injury (VILI) is a significant risk for patients with acute respiratory
distress syndrome (ARDS). Management of the patient with ARDS is currently dominated by …

Early stabilizing alveolar ventilation prevents acute respir... : Journal of Trauma and Acute Care
Surgery Early stabilizing alveolar ventilation prevents acute respiratory distress syndrome: A …