Regulation of Treg cells by cytokine signaling and co-stimulatory molecules

Y Zong, K Deng, WP Chong - Frontiers in Immunology, 2024 - frontiersin.org
CD4+ CD25+ Foxp3+ regulatory T cells (Tregs), a vital component of the immune system,
are responsible for maintaining immune homeostasis and preventing excessive immune …

[HTML][HTML] Complex Role of Regulatory T Cells (Tregs) in the Tumor Microenvironment: Their Molecular Mechanisms and Bidirectional Effects on Cancer Progression

Y Wang, J Li, S Nakahata, H Iha - International Journal of Molecular …, 2024 - mdpi.com
Regulatory T cells (Tregs) possess unique immunosuppressive activity among CD4-positive
T cells. Tregs are ubiquitously present in mammals and function to calm excessive immune …

TNF‐α can promote membrane invasion by activating the MAPK/MMP9 signaling pathway through autocrine in bone‐invasive pituitary adenoma

X Wu, L Gong, B Li, J Bai, C Li… - CNS Neuroscience & …, 2024 - Wiley Online Library
Aims A bone‐invasive pituitary adenoma exhibits aggressive behavior, leading to a worse
prognosis. We have found that TNF‐α promotes bone invasion by facilitating the …

Combined use of TLR4 and TLR7/8 agonists to improve the efficacy of immune checkpoint inhibitors in “hot” tumor treatment and the establishment of long-term …

M Wang, Q Wan, C Wang, Q Jing, Y Nie, X Zhang… - 2023 - researchsquare.com
Immunocheckpoint inhibitors, as an efficient cancer treatment, can only benefit some
patients, so it is still necessary to find a better treatment strategy. As the strongest antigen …