Natural killer (NK) cells and cytotoxic T (CD8+) cells are two of the most important types of
immune cells in our body, protecting it from deadly invaders. While the NK cell is part of the …

Previous work from this laboratory has led to the hypothesis that the stimulatory pathological
symptoms of chronic graft-vs.-host disease (GVHD) are caused by alloreactive donor T …

We reexamined two questions concerning Lyt antigens of cytotoxic T cells of the mouse: is
Lyt-1 antigen expressed on cytotoxic effector cells and can cytotoxicity be blocked by …

Mouse effector cells mediating natural cell-mediated cytotoxicity against tumor cells were
found to contain a low density of Thy 1 antigen. Treatment of nude spleen cells, or spleen …

The Ly and Ia phenotypes of T lymphocytes involved in different functions were
characterized by the use of specific antisera. T cells responsible for delayed-type …

CD8 T cells comprise a powerful branch of the adaptive immune system, yet were not
formally recognized until long after the discovery of antibody. CD8 T cells contribute to the …

In the early 1970s a spate of papers by research groups around the world provided
evidence for a negative regulatory role of thymus‐derived lymphocytes (T cells). In 1971 …

Publisher Summary This chapter discusses the multiple lymphocyte surface antigens of the
mouse. A wide range of different antigens is described, ranging from those that have a broad …

Cells bearing the T-cell differentiation alloantigens TL and Thy-1 were enumerated in
preparations of spleen and lymph node cells of nu/nu mice. Healthy nu/nu mice had few or …

The results of this study with the P815 mastocytoma confirm the results of previous studies
that showed that the passive transfer of tumor-sensitized T cells from immunized donors can …