Hibernating animals undergo a unique and reversible decrease in their whole-body
metabolism, which is often accompanied by a suppression of mitochondrial respiration …

Hibernation is a highly seasonal physiological adaptation that allows brown bears (Ursus
arctos) to survive extended periods of low food availability. Similarly, daily or circadian …

Hibernation in bears involves a suite of metabolical and physiological changes, including
the onset of insulin resistance, that are driven in part by sweeping changes in gene …

Elucidating the genetic basis of mammalian metabolism could help define mechanisms
central to health and disease. Here, we define conserved cis-regulatory elements (CREs) …

Specializations in animal diets drive selective demands on morphology, anatomy, and
physiology. Studying adaptations linked to diet evolution benefits from examining …