A bstract Direct oral anticoagulants represent a significant group of drugs used in the
prevention or treatment of venous thromboembolic events and stroke in patients with atrial …

Objectives The aim of this study is to assess micro-RNAs miR-142 and miR-39 as potential
biomarkers for drug-monitoring of rivaroxaban among elderly patients with atrial fibrillation …

Background and Objectives: Endometrial hyperplasia (EH) is a precursor lesion to
endometrial cancer (EC), and when cellular atypia is present, in 40% of cases, they are …

Während bei einer Vitamin-K-Antagonisten-Therapie die Therapieüberwachung
(International Normalized Ratio [INR]) obligat ist, gilt dies für direkte orale Antikoagulanzien …

Dabigatran, a reversible direct thrombin inhibitor, is widely used in clinical practice as a
therapeutic option due to its unique mechanism of action in comparison to other …

The paper “Routine Therapeutic Drug Monitoring of Dabigatran—Experience at a Tertiary
Center” by Chin et al, examining their experiences with monitoring dabigatran therapy over …

This work aimed at developing and validating a rapid, sensitive, and robust method of liquid
chromatography with high-resolution mass spectrometry (LC–HRMS) in parallel reaction …

Aims: Edoxaban is a direct-acting oral anticoagulant, being a highly selective, direct and
reversible factor Xa inhibitor. Edoxaban is used to treat and prevent blood clots such as …

Обоснование. Применение ингибиторов гликопротеина Р (P-gp) и носительство
определённых полиморфизмов ABCB1 могут привести к увеличению концентрации …

Stroke is a complex disorder that includes several different pathophysiological entities, and
therefore requires a personalized approach to therapy. Pharmacological acute stroke …