Cells of glioblastoma, the most frequent primary malignant brain tumor, are characterized by
their rapid growth and infiltration of adjacent healthy brain parenchyma, which reflects their …

Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …

Background Chloride intracellular channel-1 (CLIC1) activity controls glioblastoma
proliferation. Metformin exerts antitumor effects in glioblastoma stem cells (GSCs) inhibiting …

Simple Summary Glioblastoma is a devastating malignancy that has continued to prove
resistant to a variety of therapeutics. No new systemic therapy has been approved for use …

Simple Summary Electric potential patterns across tissues are instructive for development,
regeneration, and tumorigenesis because they can influence transcription, migration, and …

Simple Summary Patients with gliomas experience worsened quality of life due to epileptic
attacks. Over 80% of patients are susceptible to seizures, significantly hindering their …

Ion channels provide the basis for the nervous system's intrinsic electrical activity. Neuronal
excitability is a characteristic property of neurons and is critical for all functions of the …

Ion channels, specifically those controlling the flux of potassium across cell membranes,
have recently been shown to exhibit an important role in the pathophysiology of glioma, the …

We study the cation transport against an external concentration gradient (cation pumping)
that occurs in conical nanopores when zero-average oscillatory and white noise potentials …

Acidic extracellular pH is a major characteristic of tumor tissue, studies suggest that the local
pH value of malignant tumor tissues is between 6.0 and 6.9. Acid-sensing ion channel 1 …