Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that can lead to clinical
manifestations of systemic diseases. Its leading features include chronic synovial …

Autophagy is a degradation mechanism by which cells recycle cytoplasmic components to
generate energy. By influencing lymphocyte development, survival, and proliferation …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovitis and
destruction of cartilage, promoted by sustained inflammation. However, current treatments …

In our previous study, we explored the therapeutic effect of berberine (BBR) against IL-21/IL-
21R mediated inflammatory proliferation of adjuvant-induced arthritic fibroblast-like …

It has been long realized that the immune and skeletal systems are closely linked. This
crosstalk, also known as osteoimmunology, is a primary process required for bone health …

Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease in which
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …

Previous studies have shown that the tumor necrosis factor‐α (TNF‐α) levels in serum and
bone tissues formed in avascular necrosis of femoral head (ANFH) patients were higher …

Background Increasing evidence indicates a pathogenic role of deregulated autophagy in
rheumatoid arthritis (RA). We examined the relationship between autophagy and …

Osteoarthritis is a chronic, systemic and inflammatory disease. However, the pathogenesis
and understanding of RA are still limited. Ubiquitin-specific protease 13 (USP13) belongs to …

Autophagy is considered as an important intracellular mechanism that degrades cytoplasmic
components to furnish additional energy. It has cytoprotective effects through the …