A ROS‐Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro‐Angiogenesis for Efficient Treatment of Myocardial …
Z Zheng, C Lei, H Liu, M Jiang, Z Zhou… - Advanced …, 2022 - Wiley Online Library
Mitochondrial dysfunction of cardiomyocytes (CMs) has been identified as a significant
pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies …
pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies …
[HTML][HTML] Large animal models of cardiac ischemia-reperfusion injury: Where are we now?
Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the
efficacy of cardioprotective interventions prior to clinical translation. Nonetheless, current …
efficacy of cardioprotective interventions prior to clinical translation. Nonetheless, current …
Control of the post-infarct immune microenvironment through biotherapeutic and biomaterial-based approaches
Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for
which heart transplantation remains the only definitive treatment. IHF manifests from …
which heart transplantation remains the only definitive treatment. IHF manifests from …
[HTML][HTML] Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell …
The role of oxidative injury and inflammatory response in cardiovascular diseases and heart
failure has been well-acknowledged. This study evaluated the protective effect of …
failure has been well-acknowledged. This study evaluated the protective effect of …
Sinomenine confers protection against myocardial ischemia reperfusion injury by preventing oxidative stress, cellular apoptosis, and inflammation
B Xia, Q Li, J Wu, X Yuan, F Wang, X Lu… - Frontiers in …, 2022 - frontiersin.org
Sinomenine (SIN), an alkaloid extracted from the root of S. acutum. sinomenine, has been
shown to have antiarrhythmic, antioxidant, and anti-inflammatory effects in myocardial …
shown to have antiarrhythmic, antioxidant, and anti-inflammatory effects in myocardial …
Lagopsis supina ameliorates myocardial ischemia injury by regulating angiogenesis, thrombosis, inflammation, and energy metabolism through VEGF, ROS and …
J He, Q Zhang, X Xia, L Yang - Phytomedicine, 2023 - Elsevier
Abstract Background Lagopsis supina (Steph. ex. Willd.) Ikonn.-Gal. is an important
traditional Chinese medicine used to treat various ailments. However, its impact on …
traditional Chinese medicine used to treat various ailments. However, its impact on …
[HTML][HTML] Rap1GAP exacerbates myocardial infarction by regulating the AMPK/SIRT1/NF-κB signaling pathway
T Shan, X Li, W Xie, S Wang, Y Gao, Y Zheng, G Su… - Cellular …, 2024 - Elsevier
Abstract Rap1 GTPase-activating protein (Rap1GAP) is an important tumor suppressor. The
purpose of this study was to investigate the role of Rap1GAP in myocardial infarction (MI) …
purpose of this study was to investigate the role of Rap1GAP in myocardial infarction (MI) …
A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit
M Freeman, E Huethorst, E Boland… - American Journal …, 2024 - journals.physiology.org
Arrhythmic sudden cardiac death (SCD) is an important cause of mortality following
myocardial infarction (MI). The rabbit has similar cardiac electrophysiology to humans and is …
myocardial infarction (MI). The rabbit has similar cardiac electrophysiology to humans and is …
Transcriptome analysis of cardiac endothelial cells after myocardial infarction reveals temporal changes and long-term deficits
C Basu, PL Cannon, CP Awgulewitsch, CL Galindo… - Scientific Reports, 2024 - nature.com
Endothelial cells (ECs) have essential roles in cardiac tissue repair after myocardial
infarction (MI). To establish stage-specific and long-term effects of the ischemic injury on …
infarction (MI). To establish stage-specific and long-term effects of the ischemic injury on …
[HTML][HTML] Exercise training and experimental myocardial ischemia and reperfusion: A systematic review and meta-analysis
EC de Arruda Veiga, RF Levy, DS Bocalini… - IJC Heart & …, 2023 - Elsevier
Background Despite the success of interventional coronary reperfusion strategies, morbidity
and mortality from acute myocardial infarction are still substantial. Physical exercise is a well …
and mortality from acute myocardial infarction are still substantial. Physical exercise is a well …