Carbon dioxide supplies carbon for photosynthetic species and is a major product of
respiration for all life forms. Inside the human body where CO 2 is a by-product of the …

The sophisticated ability of living organisms to sense and respond to external stimuli is
critical for survival. This is particularly true for fungal pathogens, where the capacity to adapt …

Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited
by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop …

Cryptococcus neoformans is a ubiquitous soil fungus and airborne pathogen that causes
over 180,000 deaths each year. Cryptococcus must adapt to host CO2 levels to cause …

Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal
diseases, generally characterized by meningitis. There is a limited and not very effective …

Cryptococcus neoformans causes cryptococcal meningoencephalitis, a disease that kills
more than 180,000 people annually. Contributing to its success as a fungal pathogen is its …

Cryptococcus neoformans is a fungal pathogen of the top critical priority recognized by the
World Health Organization. This clinically important fungus also serves as a eukaryotic …

Dual-specificity LAMMER kinases are highly evolutionarily conserved in eukaryotes and
play pivotal roles in diverse physiological processes, such as growth, differentiation, and …

Fungal infections are a major contributor to morbidity and mortality among
immunocompromised populations. Moreover, fungal disease caused by molds are difficult to …

The pronounced skin tropism and pan-antifungal resistance traits of the fungal pathogen
Candida auris stand out as a serious health threat. Here, we show that a carbonic sensing …