Azole‐resistant Aspergillus fumigatus as an emerging worldwide pathogen

SM Rivelli Zea, T Toyotome - Microbiology and Immunology, 2022 - Wiley Online Library
Aspergillus fumigatus, a ubiquitous pathogen, causes aspergillosis in humans, especially in
immunodeficient patients. Azoles are frontline antifungal drugs for treating aspergillosis. The …

Aspergillosis, avian species and the one health perspective: the possible importance of birds in azole resistance

AM Melo, DA Stevens, LA Tell, C Veríssimo, R Sabino… - Microorganisms, 2020 - mdpi.com
The One Health context considers health based on three pillars: humans, animals, and
environment. This approach is a strong ally in the surveillance of infectious diseases and in …

Genomes and secretomes of Ascomycota fungi reveal diverse functions in plant biomass decomposition and pathogenesis

JF Challacombe, CN Hesse, LM Bramer, LA McCue… - BMC genomics, 2019 - Springer
Background The dominant fungi in arid grasslands and shrublands are members of the
Ascomycota phylum. Ascomycota fungi are important drivers in carbon and nitrogen cycling …

[PDF][PDF] Immobilization of Aspergillus fumigatus α-amylase via adsorption onto bentonite/chitosan for stability enhancement

Y Yandri, H Ropingi, T Suhartati, B Irawan, S Hadi - Emerg Sci J, 2023 - researchgate.net
Stability enhancement attempted in this study demonstrated that significant improvement in
the stability of the α-amylase isolated from Aspergillus fumigatus was achieved by …

Inhibition of azole-resistant Aspergillus fumigatus biofilm at various formation stages by antifungal drugs, including olorofim

L Kirchhoff, S Dittmer, DT Furnica, J Buer… - Journal of …, 2022 - academic.oup.com
Objectives Interest in aspergillosis has increased over the past decades. An increase in the
incidence of azole-resistant Aspergillus fumigatus strains has been reported; therefore, the …

The therapeutic potential of chondroitin sulfate in Aspergillus fumigatus keratitis

J Luan, X Peng, J Lin, Y Zhang, X Tian, L Zhan… - Molecular …, 2022 - Elsevier
Purpose To explore the therapeutic effect of chondroitin sulfate (CS) on Aspergillus
fumigatus (A. fumigatus) keratitis. Methods The nontoxic concentration of CS was …

Alternative non-mammalian animal and cellular methods for the study of host–fungal interactions

AM Fusco-Almeida, S de Matos Silva, KS Dos Santos… - Journal of Fungi, 2023 - mdpi.com
In the study of fungal pathogenesis, alternative methods have gained prominence due to
recent global legislation restricting the use of mammalian animals in research. The principle …

Appressorium: The Breakthrough in Dikarya

A Demoor, P Silar, S Brun - Journal of Fungi, 2019 - mdpi.com
Phytopathogenic and mycorrhizal fungi often penetrate living hosts by using appressoria
and related structures. The differentiation of similar structures in saprotrophic fungi to …

Amino sugars influence Aspergillus fumigatus cell wall polysaccharide biosynthesis, and biofilm formation through interfering galactosaminogalactan deacetylation

R He, P Wei, AS Odiba, L Gao, S Usman, X Gong… - Carbohydrate …, 2024 - Elsevier
Aspergillus fumigatus is a ubiquitous fungal pathogen responsible for a significant number
of deaths annually due to invasive aspergillosis infection. While the utilization of diverse …

Review of current and future therapeutics in ABPA

E Lewington-Gower, L Chan… - Therapeutic advances in …, 2021 - journals.sagepub.com
Allergic bronchopulmonary aspergillosis is an allergic pulmonary condition caused by
hypersensitivity to antigens of Aspergillus sp. found most commonly in patients with …