Current status and future prospects for esophageal cancer

M Sheikh, G Roshandel, V McCormack, R Malekzadeh - Cancers, 2023 - mdpi.com
Simple Summary Over 500,000 individuals died due to esophageal cancer (EC) worldwide
in 2020. More than four decades of etiological research have predominantly focused on the …

Environmental and life-style risk factors for esophageal squamous cell carcinoma in Africa: a systematic review and meta-analysis

H Simba, H Kuivaniemi, CC Abnet, G Tromp… - BMC Public Health, 2023 - Springer
Abstract Background The African Esophageal Squamous Cell Carcinoma (ESCC) corridor,
which spans from Ethiopia down to South Africa, is an esophageal cancer hotspot …

Alcohol consumption and oesophageal squamous cell cancer risk in east Africa: findings from the large multicentre ESCCAPE case-control study in Kenya, Tanzania …

DRS Middleton, BT Mmbaga, D Menya… - The Lancet Global …, 2022 - thelancet.com
Background The contribution of alcohol to the large burden of oesophageal squamous cell
carcinoma (ESCC) in east Africa remains uncertain and difficult to assess owing to complex …

A very-hot food and beverage thermal exposure index and esophageal cancer risk in Malawi and Tanzania: findings from the ESCCAPE case–control studies

G Masukume, BT Mmbaga, CP Dzamalala… - British journal of …, 2022 - nature.com
Background Consumption of very-hot beverages/food is a probable carcinogen. In East
Africa, we investigated esophageal squamous cell carcinoma (ESCC) risk in relation to four …

Risk factors associated with early-onset esophageal cancer in Tanzania

GC Buckle, EJ Mmbaga, A Paciorek, L Akoko… - JCO Global …, 2022 - ascopubs.org
PURPOSE Eastern Africa is one of several regions affected by high incidence rates of
esophageal squamous cell carcinoma (ESCC). A unique epidemiologic feature of ESCC in …

[HTML][HTML] Indoor wood combustion, carcinogenic exposure and esophageal cancer in southwest Kenya

MM Mwachiro, N Pritchett, AM Calafat, RK Parker… - Environment …, 2021 - Elsevier
Background Exposure to polycyclic aromatic hydrocarbons (PAHs) is a risk factor for
esophageal squamous cell carcinoma (ESCC) in high-incidence areas of China, Iran and …

An international report on bacterial communities in esophageal squamous cell carcinoma

J Nomburg, S Bullman… - … Journal of Cancer, 2022 - Wiley Online Library
The incidence of esophageal squamous cell carcinoma (ESCC) is disproportionately high in
the eastern corridor of Africa and parts of Asia. Emerging research has identified a potential …

The dysregulation of unsaturated fatty acid-based metabolomics in the MNNG-induced malignant transformation of Het-1A cells

H Zhang, Q Liu, C Zhao, Y Zhang, S Wang… - … Science and Pollution …, 2022 - Springer
Studies have shown that environmental carcinogens exerted an important function in the
high incidence of esophageal cancer (EC). Nitrosamines have been identified as important …

Expanding oesophageal cancer research and care in eastern Africa

Nature Reviews Cancer, 2022 - nature.com
The African Esophageal Cancer Consortium is a self-organized oesophageal cancer
research consortium of more than 80 physicians and scientists working at ten sites in nine …

[HTML][HTML] A concise review towards defining the exposome of oesophageal cancer in sub-Saharan Africa

T Lipenga, L Matumba, A Vidal, Z Herceg… - Environment …, 2021 - Elsevier
Context Oesophageal cancer (EC) is among the common causes of illness and death
among all cancers worldwide. Advanced EC has a poor prognosis, with worse outcomes …