The treatment of infantile spasms is challenging, especially in the context of the following:(1)
a severe phenotype with high morbidity and mortality;(2) the urgency of diagnosis and …

Objective To compare the efficacy and safety of the ketogenic diet (KD) with standard
adrenocorticotropic hormone (ACTH) treatment in infants with West syndrome. Methods In …

Early diagnosis and treatment are critical for young children with infantile spasms (IS), as
this maximizes the possibility of the best possible child-specific outcome. However, there are …

Objective We aimed to explore the feasibility of using scalp‐recorded high‐frequency
oscillations (HFOs) to evaluate the efficacy and prognosis of adrenocorticotropic hormone …

Purpose Limited data suggest that cannabidiol (CBD) may be effective for treatment of
refractory infantile spasms (IS). This study was designed to more rigorously evaluate the …

After initially successful treatment of infantile spasms, the long-term cumulative risk of
relapse approaches 50%, and there is no established protocol to mitigate this risk. Although …

Objective This study was undertaken to evaluate our treatment algorithm for infantile
epileptic spasms syndrome (IESS) used between 2000 and 2018. We initiated vigabatrin …

Objective. Scalp high-frequency oscillations (HFOs) are a promising biomarker of
epileptogenicity in infantile spasms (IS) and many other epilepsy syndromes, but prior …

Background There is ongoing debate regarding the comparative effectiveness of
adrenocorticotropic hormone and prednisolone in the treatment of infantile spasms. With a …

Introduction Even though adrenocorticotropic hormone (ACTH) demonstrated powerful
efficacy in the initially successful treatment of infantile spasms (IS), nearly one-half of …