Inflammatory bowel disease: a review of pre-clinical murine models of human disease

B Katsandegwaza, W Horsnell, K Smith - International Journal of …, 2022 - mdpi.com
Crohn's disease (CD) and ulcerative colitis (UC) are both highly inflammatory diseases of
the gastrointestinal tract, collectively known as inflammatory bowel disease (IBD). Although …

The role of IL-23 in the pathogenesis and therapy of inflammatory bowel disease

A Korta, J Kula, K Gomułka - International Journal of Molecular Sciences, 2023 - mdpi.com
Interleukin-23 (IL-23) is a proinflammatory cytokine produced mainly by macrophages and
antigen-presenting cells (APCs) after antigenic stimulation. IL-23 plays a significant role as a …

The treatment with interleukin 17 inhibitors and immune-mediated inflammatory diseases

L Țiburcă, M Bembea, DC Zaha, AD Jurca… - Current Issues in …, 2022 - mdpi.com
IL-17 inhibitors (IL-17i) are medicines used to treat dermatological and rheumatic diseases
They belong to a class of medicines called biological disease-modifying anti-rheumatic …

[PDF][PDF] 关于炎症性肠病发病机制的研究进展

侯晓婷, 孟欢, 薛佳辰, 张华敏, 王旭德… - 中国比较医学 …, 2023 - zgbjyx.cnjournals.com
炎症性肠病(inflammatory bowel disease, IBD) 是一种全球性的特发性疾病, 病变部位累及回肠,
直肠, 结肠. IBD 在临床早期就开始出现症状, 包括腹部不适, 腹泻, 便血, 发热, 乏力和体重减轻 …

A Narrative Review of Cytokine Networks: Pathophysiological and Therapeutic Implications for Inflammatory Bowel Disease Pathogenesis

M Vebr, R Pomahačová, J Sýkora, J Schwarz - Biomedicines, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a lifelong inflammatory immune mediated disorder,
encompassing Crohn's disease (CD) and ulcerative colitis (UC); however, the cause and …

Circulating levels of cytokines and risk of inflammatory bowel disease: evidence from genetic data

B Liu, Y Qian, Y Li, X Shen, D Ye, Y Mao… - Frontiers in …, 2023 - frontiersin.org
Background Prior epidemiological studies have established a correlation between
inflammatory cytokines and inflammatory bowel disease (IBD). However, the nature of this …

Traditional chinese medicine regulates Th17/treg balance in treating inflammatory bowel disease

F Xie, Q Xiong, Y Li, C Yao, R Wu… - Evidence‐Based …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD), also known as chronic nonspecific inflammatory disease
of the colon and rectum, is primarily characterized by mucopurulent bloody stools, diarrhea …

[HTML][HTML] Marine Algae and Deriving Biomolecules for the Management of Inflammatory Bowel Diseases: Potential Clinical Therapeutics to Decrease Gut Inflammatory …

A Repici, A Hasan, AP Capra, SA Scuderi, I Paterniti… - Marine Drugs, 2024 - mdpi.com
The term “inflammatory bowel disease”(IBD) describes a class of relapse-remitting
conditions that affect the gastrointestinal (GI) tract. Among these, Crohn's disease (CD) and …

Exploration of the core pathway of inflammatory bowel disease complicated with metabolic fatty liver and two-sample Mendelian randomization study of the causal …

Z Wei, J Wang - Frontiers in Immunology, 2024 - frontiersin.org
Background Inflammatory bowel disease (IBD) is often associated with complex
extraintestinal manifestations. The incidence of nonalcoholic fatty liver disease (NAFLD) in …

New‐Onset Crohn's Disease following Initiation of Secukinumab: A Case Report and Review of the Role of IL‐17 in the Pathogenesis of Crohn's Disease

A Khouri, C Moreno, B Niland - Case Reports in …, 2023 - Wiley Online Library
Patients with autoimmune conditions show a high expression of proinflammatory cytokines
including interleukin (IL)‐17. While IL‐17 inhibitors have demonstrated efficacy in managing …