Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome
E Stener-Victorin, V Padmanabhan… - Endocrine …, 2020 - academic.oup.com
More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …
[HTML][HTML] PCOS and role of cumulus gene expression in assessing oocytes quality
The global infertility rate has been declining from year to year. PCOS is one of the treatable
accountable causes contributing to anovulatory infertility. Nevertheless, the success rate of …
accountable causes contributing to anovulatory infertility. Nevertheless, the success rate of …
[HTML][HTML] Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura… - Cell metabolism, 2021 - cell.com
Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder
affecting women of reproductive age. PCOS has a strong heritable component, but its …
affecting women of reproductive age. PCOS has a strong heritable component, but its …
[HTML][HTML] Single-cell reconstruction of follicular remodeling in the human adult ovary
X Fan, M Bialecka, I Moustakas, E Lam… - Nature …, 2019 - nature.com
The ovary is perhaps the most dynamic organ in the human body, only rivaled by the uterus.
The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian …
The molecular mechanisms that regulate follicular growth and regression, ensuring ovarian …
[HTML][HTML] Molecular features of polycystic ovary syndrome revealed by transcriptome analysis of oocytes and cumulus cells
J Li, H Chen, M Gou, C Tian, H Wang… - Frontiers in cell and …, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) is typically characterized by a polycystic ovarian
morphology, hyperandrogenism, ovulatory dysfunction, and infertility. Furthermore, PCOS …
morphology, hyperandrogenism, ovulatory dysfunction, and infertility. Furthermore, PCOS …
Environmental toxicant induced epigenetic transgenerational inheritance of ovarian pathology and granulosa cell epigenome and transcriptome alterations: ancestral …
E Nilsson, R Klukovich, I Sadler-Riggleman, D Beck… - Epigenetics, 2018 - Taylor & Francis
Two of the most prevalent ovarian diseases affecting women's fertility and health are Primary
Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome (PCOS). Previous studies …
Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome (PCOS). Previous studies …
[HTML][HTML] Autophagy is activated in the ovarian tissue of polycystic ovary syndrome
The importance of autophagy in polycystic ovary syndrome (PCOS)-related metabolic
disorders is increasingly being recognized, but few studies have investigated the role of …
disorders is increasingly being recognized, but few studies have investigated the role of …
Transcriptomic integrity of human oocytes used in ARTs: technical and intrinsic factor effects
B Ducreux, C Patrat, J Trasler… - Human Reproduction …, 2024 - academic.oup.com
Background Millions of children have been born throughout the world thanks to ARTs, the
harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the …
harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the …
[HTML][HTML] Single-cell transcriptomic analysis reveals mitochondrial dynamics in oocytes of patients with polycystic ovary syndrome
L Qi, B Liu, X Chen, Q Liu, W Li, B Lv, X Xu… - Frontiers in …, 2020 - frontiersin.org
Polycystic ovary syndrome (PCOS), characterized by polycystic ovarian morphology, ovarian
follicular maturation arrest, and hormonal disorders, affects numerous women in the …
follicular maturation arrest, and hormonal disorders, affects numerous women in the …
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1
T Wang, Y Liu, M Lv, Q Xing, Z Zhang, X He, Y Xu… - Gene, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic heterogeneous disorder.
The incidence of which reaches 5% to 10% among reproductive-age women. Abnormal …
The incidence of which reaches 5% to 10% among reproductive-age women. Abnormal …