Targeting of potassium channels in cardiac arrhythmias

S Burg, B Attali - Trends in Pharmacological Sciences, 2021 - cell.com
Cardiomyocytes are endowed with a complex repertoire of ion channels, responsible for the
generation of action potentials (APs), travelling waves of electrical excitation, propagating …

[HTML][HTML] Anxiety, mental stress, and sudden cardiac arrest: epidemiology, possible mechanisms and future research

NM Batelaan, A Seldenrijk, OA van den Heuvel… - Frontiers in …, 2022 - frontiersin.org
Sudden cardiac arrest (SCA) is a leading cause of mortality and morbidity in affluent
societies, which underscores the need to identify persons at risk. The etiology of SCA is …

[HTML][HTML] Potassium channels, tumorigenesis and targeted drugs

C Xia, C Liu, S Ren, Y Cai, Q Zhang, C Xia - Biomedicine & …, 2023 - Elsevier
Potassium channels play an important role in human physiological function. Recently,
various molecular mechanisms have implicated abnormal functioning of potassium …

Concise review: criteria for chamber-specific categorization of human cardiac myocytes derived from pluripotent stem cells

C Kane, CMN Terracciano - Stem Cells, 2017 - academic.oup.com
Human pluripotent stem cell-derived cardiomyocytes (PSC-CMs) have great potential
application in almost all areas of cardiovascular research. A current major goal of the field is …

[HTML][HTML] Antiarrhythmic drugs for atrial fibrillation: imminent impulses are emerging

GA Dan, D Dobrev - IJC heart & vasculature, 2018 - Elsevier
Rhythm and rate strategies are considered equivalent for the management of atrial
fibrillation (AF). Moreover, both strategies are intended for improving symptoms and quality …

[HTML][HTML] TREK channels in Mechanotransduction: a Focus on the Cardiovascular System

S Herrera-Pérez, JA Lamas - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Mechano-electric feedback is one of the most important subsystems operating in the
cardiovascular system, but the underlying molecular mechanism remains rather unknown …

Ionic basis of cardiac electrophysiology in zebrafish compared to human hearts

U Ravens - Progress in biophysics and molecular biology, 2018 - Elsevier
Zebrafish heart has evolved as an intensely studied model for cardiac development,
physiology and pathophysiology. A particular advantage is its morphological and functional …

Expression of miRNAs in plasma exosomes derived from patients with atrial fibrillation

Z Wei, Z Bing, Q Shaohuan, W Yanran… - Clinical …, 2020 - Wiley Online Library
Background Studies have revealed the association between exosomes and cardiovascular
diseases. However, the typical changes of plasma miRNAs in patients with atrial fibrillation …

Atria-selective antiarrhythmic drugs in need of alliance partners

R Peyronnet, U Ravens - Pharmacological Research, 2019 - Elsevier
Atria-selective antiarrhythmic drugs in need of alliance partners. Guideline-based treatment
of atrial fibrillation (AF) comprises prevention of thromboembolism and stroke, as well as …

Photosensitive nanocarriers for specific delivery of cargo into cells

P Mena-Giraldo, S Pérez-Buitrago… - Scientific Reports, 2020 - nature.com
Nanoencapsulation is a rapidly expanding technology to enclose cargo into inert material at
the nanoscale size, which protects cargo from degradation, improves bioavailability and …