WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome

P Wang, J Ma, YC Kim, AY Son… - Proceedings of the …, 2023 - National Acad Sciences
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by various
disabling symptoms including exercise intolerance and is diagnosed in the absence of a …

Targeting WASF3 signaling in metastatic cancer

R Loveless, Y Teng - International journal of molecular sciences, 2021 - mdpi.com
Increasing evidence indicates that cancer metastasis is regulated by specific genetic
pathways independent of those controlling tumorigenesis and cancer growth. WASF3, a …

Drug resistance related genes in lung adenocarcinoma predict patient prognosis and influence the tumor microenvironment

H Yu, W Zhang, XR Xu, S Chen - Scientific Reports, 2023 - nature.com
Lung adenocarcinoma (LUAD) is the predominant type of non-small lung cancer (NSCLC)
with strong invasive ability and poor prognosis. The drug resistance related genes are …

The WASF3–NCKAP1–CYFIP1 complex is essential for breast cancer metastasis

Y Teng, H Qin, A Bahassan, NG Bendzunas… - Cancer research, 2016 - AACR
Inactivation of the WASF3 gene suppresses invasion and metastasis of breast cancer cells.
WASF3 function is regulated through a protein complex that includes the NCKAP1 and …

In Silico Optimized Stapled Peptides Targeting WASF3 in Breast Cancer

AJ Limaye, GN Bendzunas, MK Whittaker… - ACS Medicinal …, 2022 - ACS Publications
Wiskott–Aldrich Syndrome Protein Family (WASF) members regulate actin cytoskeletal
dynamics, and WASF3 is directly associated with breast cancer metastasis and invasion …

WASF3 knockdown sensitizes gastric cancer cells to oxaliplatin by inhibiting ATG12-mediated autophagy

Y Nie, X Liang, S Liu, F Guo, N Fang, F Zhou - The American Journal of the …, 2020 - Elsevier
Background Gastric cancer is one of the most aggressive tumors, usually resulting in
metastasis, and therapies for advanced gastric cancer remain limited. Drug resistance is the …

Gene expression behavior of a set of genes in platelet and tissue samples from patients with breast cancer

LA Burciaga-Hernandez, CF Cueto-Villalobos… - International Journal of …, 2023 - mdpi.com
The tumor microenvironment (TME) is constituted by a great diversity of highly dynamic cell
populations, each of which contributes ligands, receptors, soluble proteins, mRNAs, and …

[HTML][HTML] Wasf3 deficiency reveals involvement in metastasis in a mouse model of breast cancer

H Qin, S Lu, M Thangaraju, JK Cowell - The American journal of pathology, 2019 - Elsevier
The WASF3 gene has been implicated in cancer cell movement, invasion, and metastasis by
regulating genetic pathways important in these processes. Invasion and metastasis assays …

WAVE3 induces EMT and promotes migration and invasion in intrahepatic cholangiocarcinoma

Z Zhu, W Chen, X Yin, J Lai, Q Wang, L Liang… - Digestive diseases and …, 2016 - Springer
Abstract Background Wiskott–Aldrich syndrome protein family verprolin-homologous protein
3 (WAVE3) plays a critical role in cancer progression and metastasis. However, the specific …

Knockdown Wiskott-Aldrich syndrome protein family member 3 (WASF3) inhibits colorectal cancer metastasis and sensitizes to cisplatin through targeting ZNF471.

Z Zhang, Y Pan, Y Zhao, M Ren, Y Li, Y Feng, G Lu… - …, 2022 - search.ebscohost.com
Colorectal cancer (CRC) is a heterogeneous cancer, and many risk factors for colorectal
cancer have been established. For CRC metastasis, tumor cell migration, adhesion as well …