Microenvironment‐based diabetic foot ulcer nanomedicine

F Huang, X Lu, Y Yang, Y Yang, Y Li, L Kuai… - Advanced …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …

Recent advances in responsive hydrogels for diabetic wound healing

S Zhang, G Ge, Y Qin, W Li, J Dong, J Mei, R Ma… - Materials Today Bio, 2023 - Elsevier
Poor wound healing after diabetes mellitus remains a challenging problem, and its
pathophysiological mechanisms have not yet been fully elucidated. Persistent bleeding …

Engineering bacteria‐activated multifunctionalized hydrogel for promoting diabetic wound healing

Y Lu, H Li, J Wang, M Yao, Y Peng, T Liu… - Advanced Functional …, 2021 - Wiley Online Library
Engineering therapeutic angiogenesis in impaired tissues is critical for chronic wound
healing. Materials can be engineered to deliver specific biological cues that enhance …

Mechano‐activated cell therapy for accelerated diabetic wound healing

Y Shou, Z Le, HS Cheng, Q Liu, YZ Ng… - Advanced …, 2023 - Wiley Online Library
Chronic diabetic wounds are a significant global healthcare challenge. Current strategies,
such as biomaterials, cell therapies, and medical devices, however, only target a few …

Nanoparticle-based therapeutic approaches for wound healing: a review of the state-of-the-art

BHJ Gowda, S Mohanto, A Singh, A Bhunia… - Materials Today …, 2023 - Elsevier
Wound healing is a complex physiological procedure that includes diverse stages,
comprising hemostasis, inflammation, proliferation, and remodeling to reconstruct the skin …

Injectable, antibacterial, ROS scavenging and pro-angiogenic hydrogel adhesives promote chronic wound healing in diabetes via synergistic release of NMN and …

Z Liang, J Luo, S Liu, Y Gu, Z Cui, Y Zhu, Z Yu… - Chemical Engineering …, 2023 - Elsevier
Diabetic wound care continues a significant clinical problem due to the complex wound
microenvironment characterized by excessive ROS, bacterial infection, persistent …

Diabetes immunity-modulated multifunctional hydrogel with cascade enzyme catalytic activity for bacterial wound treatment

M Deng, M Zhang, R Huang, H Li, W Lv, X Lin… - Biomaterials, 2022 - Elsevier
Diabetes immunity-modulated wound treatment in response to the varied
microenvironments at different stages remains an urgent challenge. Herein, glucose oxidase …

[HTML][HTML] Therapeutic applications of electrospun nanofibers impregnated with various biological macromolecules for effective wound healing strategy–a review

L Sethuram, J Thomas - Biomedicine & Pharmacotherapy, 2023 - Elsevier
A Non-healing infected wound is an ever-growing global epidemic, with increasing burden
of mortality rates and management costs. The problems of chronic wound infections and …

[HTML][HTML] Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds

Y Hu, H Li, X Lv, Y Xu, Y Xie, L Yuwen, Y Song, S Li… - Nanoscale, 2022 - pubs.rsc.org
Diabetic wound infection is a common disease that has significantly reduced people's
quality of life. Although tremendous achievements have been made in clinical treatment, the …

Adipose‐derived mesenchymal stem cell‐derived exosomes biopotentiated extracellular matrix hydrogels accelerate diabetic wound healing and skin regeneration

Y Song, Y You, X Xu, J Lu, X Huang, J Zhang… - Advanced …, 2023 - Wiley Online Library
Wound healing is an urgent clinical challenge, particularly in the case of chronic wounds.
Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy …