Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond

JC Hsu, P Liu, Y Song, W Song, RJ Saladin… - Chemical Society …, 2024 - pubs.rsc.org
Nanomaterials exhibit significant potential for stimulating immune responses, offering both
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …

Exosome‐Inhibiting Polymeric Sonosensitizer for Tumor‐Specific Sonodynamic Immunotherapy

J Wu, J Huang, J Yu, M Xu, J Liu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Combination cancer immunotherapy based on electromagnetic energy and immunotherapy
shows potent anti‐cancer efficacy. However, as a factor that mediates tumor metastasis and …

Optical functional nanomaterials for cancer photoimmunotherapy

L Liu, Y Pan, L Ye, C Liang, X Mou, X Dong… - Coordination Chemistry …, 2024 - Elsevier
Phototherapy not only eliminates local tumors through laser irradiation but also induces
systemic immune responses against recurrent and metastatic tumors, thereby enhancing …

Activatable Janus Nanoparticles for Precise NIR‐II Bioimaging and Synergistic Cancer Therapy

J Bao, R Liu, Z Yu, Z Cheng… - Advanced Functional …, 2024 - Wiley Online Library
Despite multifunctional theranostics hold vast potential in deep tissue bioimaging and tumor
therapy, activatable nanomedicine with integration of precise diagnosis and effective …

A Comprehensive Strategy Based on High Clinical Translational Nanosystem for Programmable Immunotherapy of Triple Negative Breast Cancer

M Meng, J Wu, Y Feng, L Lin, J Chen… - Advanced …, 2024 - Wiley Online Library
Triple negative breast cancer (TNBCs), known as an immunologically cold tumor, is difficult
to completely eliminate with existing monotherapies, let alone metastasis and recurrence. It …

Toward the scale-up production of polymeric nanotherapeutics for cancer clinical trials

MM Mahmud, N Pandey, JA Winkles, GF Woodworth… - Nano Today, 2024 - Elsevier
Nanotherapeutics have gained significant attention for the treatment of numerous cancers,
primarily because they can accumulate in and/or selectively target tumors leading to …

Ultrasound-Controlled Prodrug Activation: Emerging Strategies in Polymer Mechanochemistry and Sonodynamic Therapy

X Fu, X Hu - ACS Applied Bio Materials, 2024 - ACS Publications
Ultrasound has gained prominence in biomedical applications due to its noninvasive nature
and ability to penetrate deep tissue with spatial and temporal resolution. The burgeoning …

Supramolecular prodrug-like nanotheranostics with dynamic and activatable nature for synergistic photothermal immunotherapy of metastatic cancer

Y Li, X Mu, W Feng, M Gao, Z Wang, X Bai… - Journal of Controlled …, 2024 - Elsevier
Synergistic photothermal immunotherapy has attracted widespread attention due to the
mutually reinforcing therapeutic effects on primary and metastatic tumors. However, the lack …

pH-responsive oxygen self-sufficient smart nanoplatform for enhanced tumor chemotherapy and photodynamic therapy

X Liu, X Wang, D Zang, Y Chang, W Su, G Li… - Journal of Colloid and …, 2024 - Elsevier
Premature drug release in chemotherapy and hypoxic conditions in photodynamic therapy
(PDT) are perplexing problems in tumor treatment. Thus, it is of great significance to develop …

DNA nanodevice as a multi-module co-delivery platform for combination cancer immunotherapy

C Nie, J Ye, JH Jiang, X Chu - Journal of Colloid and Interface Science, 2024 - Elsevier
A major challenge in combining cancer immunotherapy is the efficient delivery of multiple
types of immunological stimulators to elicit a robust anti-tumor immune response and …