Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
The increasing threat of Pseudomonas aeruginosa high-risk clones
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …
Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis
MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …
[HTML][HTML] Microbial dysbiosis: rethinking disease in marine ecosystems
S Egan, M Gardiner - Frontiers in microbiology, 2016 - frontiersin.org
With growing environmental pressures placed on our marine habitats there is concern that
the prevalence and severity of diseases affecting marine organisms will increase. Yet …
the prevalence and severity of diseases affecting marine organisms will increase. Yet …
[HTML][HTML] Recent advances in understanding Pseudomonas aeruginosa as a pathogen
J Klockgether, B Tümmler - F1000Research, 2017 - ncbi.nlm.nih.gov
The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen
causing acute and chronic infections in predisposed human subjects. Here we review recent …
causing acute and chronic infections in predisposed human subjects. Here we review recent …
[HTML][HTML] Repair Process Impairment by Pseudomonas aeruginosa in Epithelial Tissues: Major Features and Potential Therapeutic Avenues
M Ruffin, E Brochiero - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
Epithelial tissues protecting organs from the environment are the first-line of defense against
pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain …
pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain …
[HTML][HTML] Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium
The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …
and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic …
Insect pathogenicity in plant-beneficial pseudomonads: phylogenetic distribution and comparative genomics
P Flury, N Aellen, B Ruffner, M Péchy-Tarr… - The ISME …, 2016 - academic.oup.com
Bacteria of the genus Pseudomonas occupy diverse environments. The Pseudomonas
fluorescens group is particularly well-known for its plant-beneficial properties including …
fluorescens group is particularly well-known for its plant-beneficial properties including …
The Population Structure of Pseudomonas aeruginosa Is Characterized by Genetic Isolation of exoU+ and exoS+ Lineages
The diversification of microbial populations may be driven by many factors including
adaptation to distinct ecological niches and barriers to recombination. We examined the …
adaptation to distinct ecological niches and barriers to recombination. We examined the …
[HTML][HTML] Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis
Virulence-linked pathways in opportunistic pathogens are putative therapeutic targets that
may be associated with less potential for resistance than targets in growth-essential …
may be associated with less potential for resistance than targets in growth-essential …