Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a
peripheral hormone. Most of the body's serotonin is circulating in the bloodstream …

Scientific interest in serotonergic psychedelics (eg, psilocybin and LSD; 5‐HT2A receptor
agonists) has dramatically increased within the last decade. Clinical studies administering …

Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

Background: In the past few years, the issue of 'microdosing'psychedelics has been openly
discussed in the public arena where claims have been made about their positive effect on …

Abstract Serotonin (5-hydroxytryptamine, 5-HT) 2A receptor agonists have recently emerged
as promising new treatment options for a variety of disorders. The recent success of these …

It is estimated that 2% to 3% of the population are currently prescribed systemic or topical
glucocorticoid treatment. The potent anti-inflammatory action of glucocorticoids to deliver …

Patients characterized by stress-related disorders such as depression display elevated
circulating concentrations of pro-inflammatory cytokines and a hyperactive HPA axis …

Humans have used serotonergic hallucinogens (ie psychedelics) for spiritual, ceremonial,
and recreational purposes for thousands of years, but their administration as part of a …