Z‐ligustilide: a review of its pharmacokinetics and pharmacology
Q Xie, L Zhang, L Xie, Y Zheng, K Liu… - Phytotherapy …, 2020 - Wiley Online Library
Z‐ligustilide is a natural benzoquinone derivative found in many widely used Chinese
herbal medicines such as Angelica sinensis (Oliv.) Diels as well as Ligusticum chuanxiong …
herbal medicines such as Angelica sinensis (Oliv.) Diels as well as Ligusticum chuanxiong …
Phthalides: distribution in nature, chemical reactivity, synthesis, and biological activity
A León, M Del-Ángel, JL Ávila, G Delgado - Progress in the chemistry of …, 2017 - Springer
Phthalides are a relatively small group of natural compounds confined to several plant
families and some genera of fungi and liverworts. They are divided into two structural …
families and some genera of fungi and liverworts. They are divided into two structural …
[HTML][HTML] Knowledge Mapping of Angelica sinensis (Oliv.) Diels (Danggui) Research: A Scientometric Study
Background Traditional Chinese medicine (TCM) has been widely accepted and applied
worldwide, and many publications related to Angelica sinensis (Oliv.) Diels (AS, Chinese …
worldwide, and many publications related to Angelica sinensis (Oliv.) Diels (AS, Chinese …
Identification and determination of the major constituents in Traditional Chinese Medicinal formula Danggui-Shaoyao-San by HPLC–DAD–ESI-MS/MS
L Chen, J Qi, Y Chang, D Zhu, B Yu - Journal of Pharmaceutical and …, 2009 - Elsevier
Danggui-Shaoyao-San (DSS), a famous traditional Chinese medicine formula consisting of
six herbal medicines (Paeonia lactiflora, Angelica sinensis, Ligusticum chuanxiong, Poria …
six herbal medicines (Paeonia lactiflora, Angelica sinensis, Ligusticum chuanxiong, Poria …
Ligustilide attenuates vascular inflammation and activates Nrf2/HO-1 induction and, NO synthesis in HUVECs
ES Choi, JJ Yoon, BH Han, DH Jeong, YJ Lee… - Phytomedicine, 2018 - Elsevier
Background Ligustilide is a bioactive phthalide derivative isolated from Cnidii Rhizoma
(Cnidium officinale, rhizome) and Angelicae Gigantis Radix (Angelica gigas Nakai, root) …
(Cnidium officinale, rhizome) and Angelicae Gigantis Radix (Angelica gigas Nakai, root) …
Metabolism and pharmacokinetics of 3-n-butylphthalide (NBP) in humans: the role of cytochrome P450s and alcohol dehydrogenase in biotransformation
3-n-Butylphthalide (NBP) is a cardiovascular drug currently used for the treatment of
cerebral ischemia. The present study aims to investigate the metabolism, pharmacokinetics …
cerebral ischemia. The present study aims to investigate the metabolism, pharmacokinetics …
Epigenetic Reactivation of Nrf2 in Murine Prostate Cancer TRAMP C1 Cells by Natural Phytochemicals Z-Ligustilide and Radix Angelica Sinensis via Promoter CpG …
Cancer development has been linked to epigenetic modifications of cancer oncogenes and
tumor suppressor genes; in advanced metastatic cancers, severe epigenetic modifications …
tumor suppressor genes; in advanced metastatic cancers, severe epigenetic modifications …
Development of a three-step-based novel strategy integrating DMPK with network pharmacology and bioactivity evaluation for the discovery of Q-markers of traditional …
Q Wang, G Chen, X Chen, Y Liu, Z Qin, P Lin, H Shang… - Phytomedicine, 2023 - Elsevier
Background Quality marker (Q-marker) serves an important role in promoting the
standardization of the quality of traditional Chinese medicine (TCM) prescriptions. However …
standardization of the quality of traditional Chinese medicine (TCM) prescriptions. However …
[HTML][HTML] Senkyunolide I: a review of its phytochemistry, pharmacology, pharmacokinetics, and drug-likeness
Y Huang, Y Wu, H Yin, L Du, C Chen - Molecules, 2023 - mdpi.com
Senkyunolide I (SI) is a natural phthalide that has drawn increasing interest for its potential
as a cardio-cerebral vascular drug candidate. In this paper, the botanical sources …
as a cardio-cerebral vascular drug candidate. In this paper, the botanical sources …