Natural anti-biofilm agents: strategies to control biofilm-forming pathogens

R Mishra, AK Panda, S De Mandal, M Shakeel… - Frontiers in …, 2020 - frontiersin.org
Pathogenic microorganisms and their chronic pathogenicity are significant concerns in
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …

Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Personalized bacteriophage therapy to treat pandrug-resistant spinal Pseudomonas aeruginosa infection

T Ferry, C Kolenda, F Laurent, G Leboucher… - Nature …, 2022 - nature.com
Bone and joint infections (BJI) are one of the most difficult-to-treat bacterial infection,
especially in the era of antimicrobial resistance. Lytic bacteriophages (phages for short) are …

Alternative therapeutic strategies to treat antibiotic-resistant pathogens

CR MacNair, ST Rutherford, MW Tan - Nature Reviews Microbiology, 2024 - nature.com
Resistance threatens to render antibiotics—which are essential for modern medicine—
ineffective, thus posing a threat to human health. The discovery of novel classes of …

Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Photoactive MOF-derived bimetallic silver and cobalt nanocomposite with enhanced antibacterial activity

D Kim, KW Park, JT Park, I Choi - ACS applied materials & …, 2023 - ACS Publications
Conventional antibiotic-based treatment of bacterial infections remains one of the most
difficult challenges in medicine because of the threat of multidrug resistance caused by …

Combination of genetically diverse Pseudomonas phages enhances the cocktail efficiency against bacteria

A Naknaen, T Samernate, W Wannasrichan… - Scientific Reports, 2023 - nature.com
Phage treatment has been used as an alternative to antibiotics since the early 1900s.
However, bacteria may acquire phage resistance quickly, limiting the use of phage …

[HTML][HTML] Global strategies to combat antimicrobial resistance: a one health perspective

S Mudenda, B Chabalenge, V Daka, RL Mfune… - Pharmacology & …, 2023 - scirp.org
Background: Antimicrobial resistance (AMR) is a global health challenge that has escalated
due to the inappropriate use of antimicrobials in humans, animals, and the environment …