Following primary infection, human cytomegalovirus (HCMV) establishes lifelong latency
and periodically reactivates without causing symptoms in healthy individuals. In the absence …

Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60–
90%. HCMV is the leading cause of congenital infections and poses a great health risk to …

Human Cytomegalovirus (CMV) is a well-recognized pathogen in the context of HIV
infection, but since the roll out of ART, clinical and scientific interest in the problem of …

Background In healthy, HIV seronegative, CMV seropositive adults, a large proportion of T
cells are CMV-specific. High-level CMV-specific T cell responses are associated with …

Recent proof-of-concept randomised controlled trials have shown a causal relation between
herpes simplex virus (HSV) type 2 infection and HIV-1 replication in co-infected individuals …

Seropositivity for CMV is one of the parameters of the “immune risk profile” associated with
mortality in longitudinal studies of the very elderly and may accelerate immunosenescence …

Although invasive cytomegalovirus (CMV) disease is uncommon in the era of antiretroviral
therapy (ART), asymptomatic CMV coinfection is nearly ubiquitous in HIV infected …

Of eight human herpesviruses (HHVs), often, only herpes simplex virus types 1 (HSV-1) and
2 (HSV-2) find mention in medical literature as both of these viruses are commonly …

Both human immunodeficiency virus (HIV) and human herpesvirus (HHV) infections persist
lifelong, and almost all individuals infected with HIV are also infected with≥ 1 HHV. These …

Human cytomegalovirus is an opportunistic double-stranded DNA virus with one of the
largest viral genomes known. The 235 kB genome is divided in a unique long (UL) and a …