Application of mesoporous silica nanoparticles in cancer therapy and delivery of repurposed anthelmintics for cancer therapy

M Koohi Moftakhari Esfahani, SE Alavi, PJ Cabot… - Pharmaceutics, 2022 - mdpi.com
This review focuses on the biomedical application of mesoporous silica nanoparticles
(MSNs), mainly focusing on the therapeutic application of MSNs for cancer treatment and …

Bioresponsive drug delivery systems

SE Alavi, S Alharthi, SZ Alavi, A Raza… - Drug Discovery …, 2023 - Elsevier
In this review, we highlight the potential of stimuli-responsive drug delivery systems (DDSs)
to revolutionize healthcare. Through examining pH, temperature, enzyme, and redox …

Impact of PEGylated liposomal doxorubicin and carboplatin combination on glioblastoma

M Ghaferi, A Raza, M Koohi, W Zahra, A Akbarzadeh… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%.
Chemotherapy is a therapeutic approach to treating the disease; however, due to the …

[HTML][HTML] High cancer selectivity and improving drug release from mesoporous silica nanoparticles in the presence of human serum albumin in cisplatin, carboplatin …

ME Moghadam, M Sadeghi, H Mansouri-Torshizi… - European Journal of …, 2023 - Elsevier
In this project, drug release was examined based on the adsorption of cisplatin, carboplatin,
oxaliplatin, and oxalipalladium on aminated mesoporous silica nanoparticles (N-HMSNs) …

Hydrogel-based therapeutic coatings for dental implants

SE Alavi, N Panah, F Page, M Gholami, A Dastfal… - European Polymer …, 2022 - Elsevier
Dental implants are widely utilized to reinforce fixed or removable dental prostheses and to
replace them with normal teeth function. Hydrogel-based coatings can be used to improve …

PEG-grafted liposomes for enhanced antibacterial and antibiotic activities: An in vivo study

SE Alavi, MKM Esfahani, A Raza, H Adelnia… - NanoImpact, 2022 - Elsevier
Staphylococcus aureus (S. aureus) biofilm-associated infections are a primary concern for
public health worldwide. Current therapeutics cannot penetrate the biofilms efficiently …

Advanced drug delivery platforms for the treatment of oral pathogens

SE Alavi, A Raza, M Gholami, M Giles, R Al-Sammak… - Pharmaceutics, 2022 - mdpi.com
The oral cavity is a complex ecosystem accommodating various microorganisms (eg,
bacteria and fungi). Various factors, such as diet change and poor oral hygiene, can change …

Carboplatin niosomal nanoplatform for potentiated chemotherapy

SE Alavi, A Raza, MKM Esfahani, A Akbarzadeh… - Journal of …, 2022 - Elsevier
This study aimed to characterize a stable nano-niosome formulation, which could reduce the
adverse effects of carboplatin (CB) and improve its therapeutic efficacy in the treatment of …

β-Lactoglobulin-modified mesoporous silica nanoparticles: a promising carrier for the targeted delivery of fenbendazole into prostate cancer cells

M Koohi Moftakhari Esfahani, SE Alavi, PJ Cabot… - Pharmaceutics, 2022 - mdpi.com
The clinical utilization of fenbendazole (FBZ) as a potential anticancer drug has been limited
due to its low water solubility, which causes its low bioavailability. The development of a …

Revolutionizing Wound Healing: Exploring Scarless Solutions through Drug Delivery Innovations

SE Alavi, SZ Alavi, M Nisa, M Koohi… - Molecular …, 2024 - ACS Publications
Human skin is the largest organ and outermost surface of the human body, and due to the
continuous exposure to various challenges, it is prone to develop injuries, customarily …