The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

The skin interstitium sequesters excess Na+ and Cl–in salt-sensitive hypertension.
Mononuclear phagocyte system (MPS) cells are recruited to the skin, sense the hypertonic …

Intercellular junctions mediate adhesion and communication between adjoining endothelial
and epithelial cells. In the endothelium, junctional complexes comprise tight junctions …

Endothelial cells control the passage of plasma constituents and circulating cells from blood
to the underlying tissues. This specialized function is lost or impaired in several pathological …

Tyrosine phosphorylation of the adhesion molecule VE-cadherin is assumed to affect
endothelial junction integrity. However, it remains unclear whether tyrosine residues of VE …

Endothelial adherens junctions maintain vascular integrity. Arteries and veins differ in their
permeability but whether organization and strength of their adherens junctions vary has not …

Recirculation of fluid and cells through lymphatic vessels plays a key role in normal tissue
homeostasis, inflammatory diseases, and cancer. Despite recent advances in understanding …

Vascular endothelial (VE)-cadherin is a strictly endothelial specific adhesion molecule
located at junctions between endothelial cells. In analogy of the role of E-cadherin as major …

1. From avascular to vascular It is clear that for vasculogenesis and angiogenesis to
effectively proceed during physiological and pathological From the earliest stages, the …

The endothelium functions as a semipermeable barrier regulating tissue fluid homeostasis
and transmigration of leukocytes and providing essential nutrients across the vessel wall …