Neurological disorders are major contributors to death and disability worldwide. The
pathology of injuries and disease processes includes a cascade of events that often involve …

This article describes commonly used experimental and clinical biomarkers of neuronal
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …

TBI has been one of the top causes of death and morbidity worldwide, yet despite enormous
efforts to discover neuroprotective therapeutics for this serious disease, no beneficial …

Glutamate is the major excitatory neurotransmitter in the brain, and it is widely accepted to
play a role in synaptic plasticity and excitotoxic cell death. Glutamate binds to several …

Recent studies have revealed the connection between amino acid chirality and diseases.
We have previously reported that the gut microbiota produces various d-amino acids in a …

The aberrant accumulation of disease-specific protein aggregates accompanying cognitive
decline is a pathological hallmark of age-associated neurological disorders, also termed as …

Worldwide, populations face significant burdens from neurodegenerative disorders (NDDs),
especially Alzheimer's and Parkinson's diseases. Although there are many proposed …

Alzheimer's disease (AD) is a multifactorial neurodegenerative condition associated with
pathological accumulation of amyloid plaques and with the appearance of deposit of …

NMDA receptors (NMDARs), a prominent subtype of glutamatergic receptors, are implicated
in the pathogenesis and development of neuropsychiatric disorders such as epilepsy …

Purpose of the Review Mechanical thrombectomy (MT)–mediated endovascular
recanalization has dramatically transformed treatment and outcomes after acute ischemic …