The methylation status of plant genomic DNA influences PCR efficiency

KV Kiselev, AS Dubrovina, AP Tyunin - Journal of plant physiology, 2015 - Elsevier
During the polymerase chain reaction (PCR), which is a versatile and widely used method,
certain DNA sequences are rapidly amplified through thermocycling. Although there are …

FederatedCloudSim: a SLA-aware federated cloud simulation framework

A Kohne, M Spohr, L Nagel, O Spinczyk - Proceedings of the 2nd …, 2014 - dl.acm.org
Recent developments show that the standardization of cloud service descriptions and
exchange leads the way for the rise of cloud federations. In these federations CSPs (cloud …

DNA methylation and cancer

G Gokul, S Khosla - Epigenetics: development and disease, 2012 - Springer
Cancer has been considered a genetic disease with a wide array of well-characterized gene
mutations and chromosomal abnormalities. Of late, aberrant epigenetic modifications have …

Epigenetic regulation in medulloblastoma

J Yi, J Wu - Molecular and Cellular Neuroscience, 2018 - Elsevier
Medulloblastoma is the most common malignant childhood brain tumor. The heterogeneous
tumors are classified into four subgroups based on transcription profiles. Recent …

[HTML][HTML] Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors

M Marotta, T Onodera, J Johnson, GT Budd… - Scientific reports, 2017 - nature.com
Oncogene amplification confers a growth advantage to tumor cells for clonal expansion.
There are several, recurrently amplified oncogenes throughout the human genome …

The epigenetics of brain tumors

AM Dubuc, S Mack, A Unterberger, PA Northcott… - … : Methods and Protocols, 2012 - Springer
Glioblastoma, medulloblastoma, and ependymoma represent molecularly and clinically
diverse forms of adult and pediatric brain tumors. While each tumor displays genetic …

Transitioning from genotypes to epigenotypes: why the time has come for medulloblastoma epigenomics

NV Batora, D Sturm, DTW Jones, M Kool, SM Pfister… - Neuroscience, 2014 - Elsevier
Recent advances in genomic technologies have allowed for tremendous progress in our
understanding of the biology underlying medulloblastoma, a malignant childhood brain …

[HTML][HTML] Targeting hedgehog pathway and DNA methyltransferases in uterine leiomyosarcoma cells

N Garcia, A Al-Hendy, EC Baracat, KC Carvalho… - Cells, 2020 - mdpi.com
Uterine leiomyosarcoma (LMS) is an aggressive tumor that presents a poor prognosis, high
rates of recurrence, and metastasis. Because of its rarity, there is no information available …

Electrogenerated chemiluminescence biosensing method for the detection of DNA methylation and assay of the methyltransferase activity

Y Li, C Huang, J Zheng, H Qi - Biosensors and Bioelectronics, 2012 - Elsevier
A novel electrogenerated chemiluminescence (ECL) biosensing method for highly sensitive
detection of DNA methylation and assay of the CpG methyltransferase (M. SssI) activity was …

[HTML][HTML] Signaling pathway and molecular subgroups of medulloblastoma

KKW Li, KM Lau, HK Ng - International journal of clinical and …, 2013 - ncbi.nlm.nih.gov
Medulloblastoma (MB) is the most common malignant brain tumor in children. Although
multimodality treatment regimens including surgery, radiotherapy and chemotherapy have …